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就诊时心脏生物标志物显著升高但心室功能正常:心肌炎表现的一种新型临床亚组。

Markedly Elevated Cardiac Bio-Markers at Presentation With Normal Ventricular Function: A Novel Clinical Subset of Myocarditis Manifestation.

作者信息

Palla Amruth R, Sontineni Siva, Mani Susan

机构信息

Danbury Hospital, Department of Internal Medicine, USA.

Creighton University School of Medicine, Department of Cardiology, USA.

出版信息

Cardiol Res. 2011 Jun;2(3):123-126. doi: 10.4021/cr15w. Epub 2011 May 20.

Abstract

We present a case of a 19-year-old woman with myocarditis who had significantly elevated cardiac markers at presentation even before any myocardial damage ensued. The patient had complicated clinical course with ventricular arrhythmia and cardiac arrest requiring resuscitation but eventually recovered completely. Though there is limited information available regarding such cases, the significantly elevated initial cardiac markers in the absence of left ventricular decompensation may probably represent a clinical subset of myocarditis and may portend an impending complicated clinical course. Further systematic research is required to define the clinical phenotype and elucidate underlying mechanisms.

摘要

我们报告一例19岁心肌炎女性病例,该患者在出现任何心肌损伤之前,就诊时心脏标志物就显著升高。患者临床过程复杂,出现室性心律失常和心脏骤停,需要进行复苏,但最终完全康复。尽管关于此类病例的信息有限,但在无左心室功能不全的情况下,初始心脏标志物显著升高可能代表心肌炎的一种临床亚型,且可能预示即将出现复杂的临床过程。需要进一步进行系统研究以明确临床表型并阐明潜在机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f6e/5358316/2c92b0a0fcb0/cr-02-123-g001.jpg

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