Cetin Mustafa, Ucar Ozgul, Canbay Alper, Cetin Zehra Guven, Cicekcioglu Hulya, Diker Erdem
Ataturk Chest Disease and Chest Surgery Education and Research Hospital, Department of Cardiology, Sanatoryum Caddesi, 06280, Ankara, Turkey.
Ankara Numune Education and Research Hospital, Department of Cardiology, Talatpasa Bulvari, 06110, Ankara, Turkey.
Cardiol Res. 2011 Jun;2(3):132-135. doi: 10.4021/cr46w. Epub 2011 May 20.
Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden cardiac death in young people. Implantable cardioverter defibrillator (ICD) is the optimal therapy in patients with HCM, both for primary or secondary prevention of sudden death. Left ventricular systolic function in HCM is usually normal. However, in few patients, HCM has been reported to progress to a state that is characterized by left ventricular dilation and systolic dysfunction, resembling dilated cardiomyopathy (DCM). Although arrhythmias are common in HCM, advanced or complete atrioventricular block (AV) is very rare. This case report describes a HCM patient who progressed to DCM with advanced AV block and survived 31 years following cardiac arrest without ICD protection.
肥厚型心肌病（HCM）是年轻人心脏性猝死最常见的原因。植入式心脏复律除颤器（ICD）是HCM患者的最佳治疗方法，可用于猝死的一级或二级预防。HCM患者的左心室收缩功能通常正常。然而，少数患者的HCM已发展为以左心室扩张和收缩功能障碍为特征的状态，类似于扩张型心肌病（DCM）。虽然心律失常在HCM中很常见，但高级或完全性房室传导阻滞（AV）非常罕见。本病例报告描述了一名HCM患者，其发展为伴有高级AV阻滞的DCM，在心脏骤停后未接受ICD保护的情况下存活了31年。
