Azeem Mohammad Irfan, Tashani Mohamed, Badahdah Al-Mamoon, Heron Leon, Pedersen Kristen, Jeoffreys Neisha, Kok Jen, Haworth Elizabeth, Dwyer Dominic E, Hill-Cawthorne Grant, Rashid Harunor, Booy Robert
Mohammad Irfan Azeem, Mohamed Tashani, Al-Mamoon Badahdah, Leon Heron, Harunor Rashid, Robert Booy, National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, Kids Research Institute, the Children's Hospital at Westmead, Sydney 2145, Australia.
World J Clin Cases. 2017 Mar 16;5(3):102-111. doi: 10.12998/wjcc.v5.i3.102.
To estimate the pharyngeal carriage rate of (), () and () among Australian Hajj pilgrims.
In 2014, surveillance was conducted in two phases among Australian Hajj pilgrims: The first phase during Hajj in Mina, and the second phase soon after returning home to Australia. Nasopharyngeal or oropharyngeal swabs were taken from participants then tested, firstly by nucleic acid testing, and also by standard culture.
Of 183 participants recruited in the first phase, 26 (14.2%) tested positive for ; 4 had received pneumococcal conjugate vaccine (PCV13). Only one tested positive for (W). Of 93 2 phase samples cultured, 17 (18.3%) grew , all methicillin sensitive, 2 (2.2%) grew (on subculture; one serotype B, one negative), and 1 (1%), from an unvaccinated pilgrim, grew .
Relatively high carriage of and little meningococcal carriage was found. This indicates the importance of a larger study for improved infection surveillance and possible vaccine evaluation.
评估澳大利亚朝觐朝圣者中（）、（）和（）的咽部携带率。
2014年，对澳大利亚朝觐朝圣者进行了两个阶段的监测：第一阶段在米纳朝觐期间，第二阶段在返回澳大利亚后不久。从参与者那里采集鼻咽或口咽拭子，然后首先通过核酸检测，也通过标准培养进行检测。
在第一阶段招募的183名参与者中，26人（14.2%）检测出（）呈阳性；4人接种过肺炎球菌结合疫苗（PCV13）。只有1人检测出（W）呈阳性。在93份第二阶段培养的样本中，17份（18.3%）培养出（），均对甲氧西林敏感，2份（2.2%）培养出（）（传代培养时；一份为B型血清型，一份为阴性），1份（1%）从未接种疫苗的朝圣者身上培养出（）。
发现（）携带率相对较高，脑膜炎球菌携带率较低。这表明开展更大规模研究以改善感染监测和可能进行疫苗评估的重要性。
