Althaus I W, Dolak L, Reusser F
Upjohn Company, Kalamazoo, MI 49001.
J Antibiot (Tokyo). 1988 Mar;41(3):373-6. doi: 10.7164/antibiotics.41.373.
Chlorobiocic acid and 3-(carbobenzoxyamino)-4,7-dihydroxy-8-methylcoumarin were identified as two new inhibitors of Micrococcus luteus DNA gyrase. Both compounds possess weak antibacterial activity against whole M. luteus cells which indicates that they probably lack efficient transport functions to penetrate the cell envelope.
氯生物环酸和3-（苄氧羰基氨基）-4,7-二羟基-8-甲基香豆素被鉴定为两种新型的藤黄微球菌DNA促旋酶抑制剂。这两种化合物对藤黄微球菌全细胞均具有微弱的抗菌活性，这表明它们可能缺乏有效的转运功能来穿透细胞壁。
