皮肤异常性疼痛在慢性偏头痛中更为常见，其出现及严重程度似乎与疾病持续时间更为相关。
Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease.
作者信息
Benatto Mariana Tedeschi, Florencio Lidiane Lima, Carvalho Gabriela Ferreira, Dach Fabíola, Bigal Marcelo Eduardo, Chaves Thaís Cristina, Bevilaqua-Grossi Débora
机构信息
Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Biomecânica, Medicina e Reabilitação do Aparelho Locomotor, Programa de Pós-Graduação em Reabilitação em Desempenho Funcional, Ribeirão Preto SP, Brasil.
Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brasil.
出版信息
Arq Neuropsiquiatr. 2017 Mar;75(3):153-159. doi: 10.1590/0004-282X20170015.
OBJECTIVE
To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic.
METHODS
80 subjects with episodic migraine and 80 with chronic migraine were assessed in a tertiary hospital. The 12-item Allodynia Symptom Checklist/Brazil questionnaire was applied to classify subjects according to the presence and severity of cutaneous allodynia.
RESULTS
Cutaneous allodynia was identified in 81.3% of the episodic migraine group and 92.5% of the chronic migraine group (p = 0.03). No increased association could be attributed to chronic migraine when adjusted by years with disease (PR = 1.12; 95%CI = 0.99 to 1.27; p = 0.06). The groups also did not differ in the severity of allodynia, and severe presentation was the most frequent.
DISCUSSION
Both groups seemed to be similarly affected in the cephalic and extracephalic regions, with the same severity.
CONCLUSION
Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease.
目的
在一家三级头痛诊所评估慢性偏头痛和发作性偏头痛患者的皮肤异常性疼痛。
方法
在一家三级医院对80名发作性偏头痛患者和80名慢性偏头痛患者进行评估。应用12项异常性疼痛症状清单/巴西问卷，根据皮肤异常性疼痛的存在和严重程度对受试者进行分类。
结果
发作性偏头痛组中81.3%的患者以及慢性偏头痛组中92.5%的患者存在皮肤异常性疼痛（p = 0.03）。按患病年限进行调整后，慢性偏头痛并未显示出更强的相关性（PR = 1.12；95%CI = 0.99至1.27；p = 0.06）。两组在异常性疼痛的严重程度方面也没有差异，严重表现最为常见。
讨论
两组在头部和头部以外区域似乎受到了相似程度的影响，严重程度相同。
结论
皮肤异常性疼痛在慢性偏头痛中更为常见，其存在和严重程度似乎与疾病持续时间更相关。
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