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口腔鳞状细胞癌患者颈部淋巴结转移的术前评估:触诊、超声检查和计算机断层扫描效能的比较研究

Preoperative evaluation of cervical lymph nodes for metastasis in patients with oral squamous cell carcinoma: A comparative study of efficacy of palpation, ultrasonography and computed tomography.

作者信息

Mishra Niranjan, Rath Krushna Chandra, Upadhyay Upendra Nath, Raut Subhrajit, Baig Shadab Ali, Birmiwal Krishna Gopal

机构信息

Department of Oral and Maxillofacial Surgery, SCB Dental College and Hospital, Cuttack, Odisha, India.

Department of Oral and Maxillofacial Surgery, City Hospital, Berhampur, Ganjam, Odisha, India.

出版信息

Natl J Maxillofac Surg. 2016 Jul-Dec;7(2):186-190. doi: 10.4103/0975-5950.201368.

DOI:10.4103/0975-5950.201368
PMID:28356691
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5357936/
Abstract

INTRODUCTION

Oral cancer is a major health threat in a country like India, where patients frequently present with advanced disease with regional dissemination to cervical lymph nodes. The management and prognosis depend on the status of cervical lymph nodes. Thus, it becomes imperative to diagnose and evaluate them preoperatively.

AIM

This study aims to compare the efficacy of palpation, ultrasonography (USG) and computed tomography (CT) in the preoperative evaluation of cervical lymph node for metastasis in patients with oral squamous cell carcinoma.

SETTINGS

Department of Oral and Maxillofacial Surgery, SCB Dental College and Hospital, Cuttack, Odisha, India.

METHODOLOGY

A total of thirty patients of either sex of age group 20-70 years, diagnosed with oral cancer were randomly selected for the study and subjected to palpation, USG and computer tomography followed by histopathology for confirmation. The results were evaluate statistically by sensitivity, specificity, positive predictive value, and negative predictive value and accuracy.

RESULTS

For level IA palpation, USG and CT were equally sensitive (100%) and specific (100%). Although palpation, USG and CT were equally sensitive (80%) for level IB, the specificity of palpation (70%) <USG (95%) = CT (95%). For level II sensitivity of palpation (25%) <USG (75%) <CT (100%) whereas specificity was CT (84.6%) <palpation (92.3%) <USG (100%).

CONCLUSION

CT (96.1%) and USG (97.7%) were more accurate than palpation (92.7%), for detection of metastasis in cervical lymph nodes in patients with oral squamous cell carcinoma. CT along with USG should be used for accurate preoperative evaluation of cervical lymph node.

摘要

引言

在印度这样的国家,口腔癌是一项重大的健康威胁,该国患者常常表现为疾病进展且区域扩散至颈部淋巴结。治疗和预后取决于颈部淋巴结的状况。因此,术前对其进行诊断和评估变得至关重要。

目的

本研究旨在比较触诊、超声检查(USG)和计算机断层扫描(CT)在口腔鳞状细胞癌患者术前评估颈部淋巴结转移方面的效果。

研究地点

印度奥里萨邦科塔克市SCB牙科学院及医院口腔颌面外科。

方法

总共随机选取30名年龄在20 - 70岁之间、被诊断为口腔癌的患者参与本研究,对其进行触诊、超声检查和计算机断层扫描,随后进行组织病理学检查以确诊。通过敏感性、特异性、阳性预测值、阴性预测值和准确性对结果进行统计学评估。

结果

对于IA区,触诊、超声检查和CT的敏感性(100%)和特异性(100%)相同。对于IB区,虽然触诊、超声检查和CT的敏感性均为80%,但触诊的特异性(70%)<超声检查(95%) = CT(95%)。对于II区,触诊敏感性(25%)<超声检查(75%)<CT(100%),而特异性方面CT(84.6%)<触诊(92.3%)<超声检查(100%)。

结论

在检测口腔鳞状细胞癌患者颈部淋巴结转移方面,CT(96.1%)和超声检查(97.7%)比触诊(92.7%)更准确。CT和超声检查应联合用于颈部淋巴结的准确术前评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f0/5357936/fbb5327e192e/NJMS-7-186-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f0/5357936/5648e3d3e98d/NJMS-7-186-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f0/5357936/fbb5327e192e/NJMS-7-186-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f0/5357936/5648e3d3e98d/NJMS-7-186-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39f0/5357936/fbb5327e192e/NJMS-7-186-g002.jpg

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