Hallur Neelakamal, Sathar Reju, Siddiqua Aaisha, Zakaullah Syed, Kothari Chaitanya
Al-Badar Rural Dental College and Hospital, Sy. No. 12, GDA Layout, Dariyapur, Naganhalli Road, Kalaburagi, Karnataka 585102 India.
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):5921-5926. doi: 10.1007/s12070-021-02495-y. Epub 2021 Apr 15.
All the head and neck tumours, more than 90% are squamous cell carcinomas (SCC). The presence of metastatic cervical lymph nodes histologically positive for SCC provides one of the simplest and most important prognostic factor in patients with head and neck cancer. In this study, all patients were examined clinically for, location, number, size, shape, consistency and fixation of cervical neck nodes to the underlying structure, and the same was carried out by FNAC, USG and CT. Findings of these modalities and histopathological results were compared for the overall metastases of lymph nodes in the neck. The accuracy of clinical examination was 87.77% and sensitivity only 41.66%. FNAC has the greatest specificity, 98.71% and least sensitivity, 33.33%. The accuracy of FNAC was 90%. The positive predictive value and negative predictive value of FNAC were 80.0% and 90.58% respectively. USG revealed 50% of sensitivity. Specificity of USG was 93.58% and accuracy 87.77%. CT scan have the highest sensitivity among all other tests, 66.66%.The negative predictive value for CT scan was also the highest, 94.59%. Specificity and accuracy of CT scan was 89.74% and 86.66% respectively. This study concludes that USG with FNAC is the most accurate in evaluating metastatic lymph nodes in oral squamous cell carcinoma patients along with other investigations like CT scan for staging of the oral squamous cell carcinoma.
所有头颈肿瘤中,超过90%为鳞状细胞癌(SCC)。组织学检查显示转移性颈部淋巴结为SCC阳性,是头颈癌患者最简单且最重要的预后因素之一。在本研究中,对所有患者进行了颈部淋巴结的临床检查,包括其位置、数量、大小、形状、质地以及与深部结构的粘连情况,并通过细针穿刺抽吸活检(FNAC)、超声检查(USG)和计算机断层扫描(CT)进行了同样的检查。将这些检查方法的结果与颈部淋巴结转移的组织病理学结果进行比较,以评估颈部淋巴结的整体转移情况。临床检查的准确率为87.77%,敏感性仅为41.66%。FNAC具有最高的特异性,为98.71%,但敏感性最低,为33.33%。FNAC的准确率为90%。FNAC的阳性预测值和阴性预测值分别为80.0%和90.58%。超声检查的敏感性为50%。超声检查的特异性为93.58%,准确率为87.77%。CT扫描在所有其他检查中具有最高的敏感性,为66.66%。CT扫描的阴性预测值也最高,为94.59%。CT扫描的特异性和准确率分别为89.74%和86.66%。本研究得出结论,对于口腔鳞状细胞癌患者,超声检查联合FNAC在评估转移性淋巴结方面最为准确,同时CT扫描等其他检查可用于口腔鳞状细胞癌的分期。