小儿非酒精性脂肪性肝病
Pediatric Non-Alcoholic Fatty Liver Disease.
作者信息
Delvin Edgard, Patey Natasha, Dubois Josée, Henderson Melanie, Lévy Émile
机构信息
Departement of Biochemistry, University of Montreal, Montreal, Quebec, Canada; CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, Canada.
CHU Sainte-Justine Research Center, University of Montreal, Montreal, Quebec, Canada; Department of Pathology, CHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada; Department of Cell Biology and Pathology, University of Montreal, Montreal, Quebec, Canada.
出版信息
J Med Biochem. 2015 Jan;34(1):3-12. doi: 10.2478/jomb-2014-0059. Epub 2014 Oct 8.
The rapidly increasing prevalence of childhood obesity and its associated co-morbidities such as hypertriglyceridemia, hyper-insulinemia, hypertension, early atherosclerosis, metabolic syndrome, and non-alcoholic fatty liver disease are major public health concerns in many countries. Therefore the trends in child and adolescent obesity should be closely monitored over time, as in the near future, we may anticipate a major increase of young adults with the stigmata of the metabolic syndrome, and of the related non-alcoholic fatty liver disease (NAFLD), that may lead to non-alcoholic steatohepatitis.
儿童肥胖症及其相关合并症（如高甘油三酯血症、高胰岛素血症、高血压、早期动脉粥样硬化、代谢综合征和非酒精性脂肪性肝病）的患病率迅速上升，是许多国家主要的公共卫生问题。因此，应长期密切监测儿童和青少年肥胖的趋势，因为在不久的将来，我们可能预计患有代谢综合征体征以及相关非酒精性脂肪性肝病（NAFLD）的年轻人会大幅增加，这可能会导致非酒精性脂肪性肝炎。
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