Kong Jie, Yang Hong-Yu, Wang Yu-Fan, Yang Hui-Jun, Shen Shi-Yue, Wang Feng
Department of Oral and Maxillofacial Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China; Peking University Shenzhen Hospital Clinical College, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
Department of Oral and Maxillofacial Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, P.R. China.
Mol Clin Oncol. 2017 Feb;6(2):214-220. doi: 10.3892/mco.2017.1126. Epub 2017 Jan 10.
The purpose of the present article was to describe the diagnostic evaluation of, and surgical approaches to, lateral skull base tumors (LSBTs). The study is a retrospective review of 21 patients diagnosed with tumors that involve lateral skull base (8 with malignant diseases and 13 with benign lesions) who were surgically treated during a 8-year period. The transparotid-transmandibular (38%) was the most commonly performed surgical procedure, followed by the transmandibular (24%), the transmaxillary (24%), the transcervical approach (10%) and the combined approach (4%). The surgical procedures were uneventful and there were no postoperative mortalities. Complications were encountered in 12 cases, and morbidity was not remarkable during the perioperative stages. After an average follow-up of 46 months, only 1 of 14 patients with benign diseases had a recurrence following the resection of a pleomorphic adenoma. Of 7 patients with malignant tumors, 5 are alive with no evidence of disease. The majority of the benign lateral skull base tumors can be removed surgically with a low rate of complications and recurrence. However, malignant neoplasms carry a poor prognosis and a low rate of disease-free survival.
本文旨在描述侧颅底肿瘤（LSBTs）的诊断评估及手术入路。该研究是对21例被诊断为累及侧颅底肿瘤的患者进行的回顾性分析（8例为恶性疾病，13例为良性病变），这些患者在8年期间接受了手术治疗。经腮腺-经下颌骨入路（38%）是最常施行的手术方式，其次是经下颌骨入路（24%）、经上颌骨入路（24%）、经颈入路（10%）和联合入路（4%）。手术过程顺利，无术后死亡病例。12例出现并发症，围手术期发病率不显著。平均随访46个月后，14例良性疾病患者中仅1例在多形性腺瘤切除术后复发。7例恶性肿瘤患者中，5例存活且无疾病证据。大多数良性侧颅底肿瘤可通过手术切除，并发症和复发率较低。然而，恶性肿瘤预后较差，无病生存率较低。
