Ni Z L, Tan X D, Shao H Y, Wang Y
School of Public Health, Wuhan University,Wuhan 430071,Hubei,China.
Epidemiol Infect. 2017 Jul;145(9):1763-1772. doi: 10.1017/S0950268817000589. Epub 2017 Mar 30.
Many parents move from rural China to urban areas in search of job opportunities, and leave their children behind to be raised by relatives. We aimed to assess the immunisation coverage, including the 1:3:3:3:1 vaccine series (one dose of Bacilli Chalmette-Guérin vaccine; three doses of live attenuated oral poliomyelitis vaccine; three doses of diphtheria, tetanus and pertussis combined; three doses of hepatitis B vaccine; and one dose of measles-containing vaccine), in children aged 12-72 months and identify the determinants of immunisation uptake among left-behind children in Hubei Province, Central China, in 2014. In this cross-sectional study using the World Health Organization's cluster sampling technique, we surveyed 1368 children from 44 villages in 11 districts of Hubei Province. The socio-demographic and vaccination status data were collected by interviewing primary caregivers using a semi-structured questionnaire and reviewing the immunisation cards of the children. Univariate and multivariate analyses were used to identify the determinants of complete vaccination and age-appropriate vaccination. For each dose of the five vaccines, the vaccination coverage in the left-behind and non-left-behind children was >90%; however, the age-appropriate vaccination coverage for each vaccine was lower in left-behind than in non-left-behind children. For the five vaccines, the fully vaccinated rate of left-behind children were lower than those of non-left-behind children (89·1%, 92·7%; P = 0·013) and age-appropriate immunisation rate of left-behind children were lower than those of non-left-behind children (65·7%, 79·9%; P < 0·001). After controlling for potential confounders, we found that the parenting pattern, annual household income and attitude of the primary caregiver towards vaccination significantly influenced the vaccination status of children. Moreover, we noted a relatively high prevalence of delayed vaccination among left-behind children. Hence, we believe that the age-appropriate immunisation coverage rate among left-behind children in rural areas should be further improved by delivering and sustaining primary care services.
许多中国农村家长前往城市寻找工作机会,将孩子留在农村由亲属抚养。我们旨在评估2014年中国中部湖北省12至72月龄儿童的免疫接种覆盖率,包括1:3:3:3:1疫苗系列(一剂卡介苗;三剂口服脊髓灰质炎减毒活疫苗;三剂白喉、破伤风和百日咳联合疫苗;三剂乙型肝炎疫苗;一剂含麻疹疫苗),并确定留守儿童免疫接种的影响因素。在这项采用世界卫生组织整群抽样技术的横断面研究中,我们调查了湖北省11个区44个村庄的1368名儿童。通过使用半结构化问卷对主要照料者进行访谈并查阅儿童免疫接种卡,收集社会人口统计学和疫苗接种状况数据。采用单因素和多因素分析确定全程接种和适龄接种的影响因素。对于五种疫苗的每剂接种,留守儿童和非留守儿童的接种覆盖率均>90%;然而,每种疫苗的适龄接种覆盖率在留守儿童中低于非留守儿童。对于这五种疫苗,留守儿童的全程接种率低于非留守儿童(89.1%,92.7%;P = 0.013),适龄免疫接种率也低于非留守儿童(65.7%,79.9%;P < 0.001)。在控制潜在混杂因素后,我们发现养育方式、家庭年收入以及主要照料者对疫苗接种的态度显著影响儿童的疫苗接种状况。此外,我们注意到留守儿童中疫苗接种延迟的患病率相对较高。因此,我们认为应通过提供并持续开展初级保健服务,进一步提高农村留守儿童的适龄免疫接种覆盖率。