Clayton Zachary S, Fusco Elizabeth, Kern Mark
Department of Human Physiology, University of Oregon, Eugene, OR.
United States Olympic Committee, Chula Vista, CA.
Nutrition. 2017 May;37:79-85. doi: 10.1016/j.nut.2016.12.014. Epub 2016 Dec 29.
Cardiovascular disease is the leading cause of death in the United States. Until recently, reducing dietary cholesterol has been a part of the American Heart Association (AHA) and American College of Cardiology (ACC) guidelines on lifestyle management, despite inconclusive evidence to support the recommendation. Considering eggs are a rich source of dietary cholesterol (typically containing 141-234 mg per egg), individuals with increased risk for CVD are advised not to consume eggs. Furthermore, based on the 2012 AHA/ACC guidelines, individuals with lower risk for CVD have previously been advised to avoid consuming eggs due to the high content of dietary cholesterol. Rather than strictly limiting cholesterol intake, the AHA and ACC guidelines now recommend dietary patterns that emphasize fruits, vegetables, whole grains, low-fat dairy products, poultry, fish, and nuts as an approach to favorably alter blood lipid levels. Of note, the 2015-2020 Dietary Guidelines for Americans have removed the recommendation of limiting cholesterol intake to no more than 300 mg per day; however, the guidelines advise that individuals should eat as little dietary cholesterol as possible while consuming a healthy eating pattern. The purpose of this review is to summarize the documented health risks of egg consumption in individuals with low and high risk for CVD and determine whether current recommendations are warranted based on the available literature. We also aim to provide guidance for future studies that will help further elucidate the health modulating effect of eggs.
心血管疾病是美国的主要死因。直到最近,减少膳食胆固醇一直是美国心脏协会(AHA)和美国心脏病学会(ACC)生活方式管理指南的一部分,尽管支持该建议的证据尚无定论。鉴于鸡蛋是膳食胆固醇的丰富来源(通常每个鸡蛋含有141 - 234毫克),心血管疾病风险增加的个体被建议不要食用鸡蛋。此外,根据2012年AHA/ACC指南,心血管疾病风险较低的个体此前也因膳食胆固醇含量高而被建议避免食用鸡蛋。美国心脏协会和美国心脏病学会的指南现在不再严格限制胆固醇摄入,而是推荐强调水果、蔬菜、全谷物、低脂乳制品、家禽、鱼类和坚果的饮食模式,以此作为有利改变血脂水平的方法。值得注意的是,2015 - 2020年《美国人膳食指南》已经取消了每天胆固醇摄入量限制在不超过300毫克的建议;然而,该指南建议个体在采用健康饮食模式的同时应尽可能少吃膳食胆固醇。本综述的目的是总结已记录的心血管疾病低风险和高风险个体食用鸡蛋的健康风险,并根据现有文献确定当前的建议是否合理。我们还旨在为未来的研究提供指导,以帮助进一步阐明鸡蛋对健康的调节作用。