1023例创伤患者的大麻和酒精使用情况。一项前瞻性研究。

Marijuana and alcohol use among 1023 trauma patients. A prospective study.

作者信息

Soderstrom C A, Trifillis A L, Shankar B S, Clark W E, Cowley R A

机构信息

Department of Surgery/Traumatology, Maryland Institute for Emergency Medical Services Systems, Baltimore 21201-1595.

出版信息

Arch Surg. 1988 Jun;123(6):733-7. doi: 10.1001/archsurg.1988.01400300079013.

DOI:10.1001/archsurg.1988.01400300079013

PMID:2835941

Abstract

Marijuana use prior to injury was determined prospectively in 1023 patients injured as the result of vehicular (67.6%) and nonvehicular (32.4%) trauma. Most were men (72.8%); most were 30 years of age or younger (58.4%). All were admitted directly from the scene of injury. Serum delta-9-tetrahydrocannabinol activity was ascertained using a radioimmunoassay. Activity of 2 ng/mL or more was detected in 34.7% of subjects. Blood alcohol determinations were made in 1006 patients; 33.5% were positive. Marijuana use among vehicular and nonvehicular trauma victims was not significantly different. Marijuana use was higher among those 30 years of age or younger and among men. Vehicular crash victims consumed alcohol more frequently. Use of marijuana and alcohol in combination (16.5%) was highly significant compared with marijuana alone (18.3%), alcohol alone (16.1%), or neither drug (49.1%).

摘要

前瞻性地确定了1023名因交通（67.6%）和非交通（32.4%）创伤而受伤患者受伤前是否使用大麻。大多数为男性（72.8%）；大多数年龄在30岁及以下（58.4%）。所有患者均从受伤现场直接入院。使用放射免疫分析法测定血清δ-9-四氢大麻酚活性。34.7%的受试者检测到活性为2 ng/mL或更高。对1006名患者进行了血液酒精测定；33.5%呈阳性。交通和非交通创伤受害者中使用大麻的情况无显著差异。30岁及以下人群和男性中使用大麻的比例更高。交通碰撞受害者饮酒更频繁。与单独使用大麻（18.3%）、单独使用酒精（16.1%）或两种药物都不使用（49.1%）相比，同时使用大麻和酒精（16.5%）的情况非常显著。