Korkmaz Bektaş, Yildiz Serpil, Yildiz Nebil
Department of Neurology, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
Department of Neurology, Abant İzzet Baysal University Faculty of Medicine, Bolu, Turkey.
Noro Psikiyatr Ars. 2015 Jun;52(2):151-156. doi: 10.5152/npa.2015.7601. Epub 2015 Jun 1.
In this study, in patients with unilateral migraine headache and in normal controls, it was aimed to assess the sympathetic function during attack, post attack, and interval periods and to compare these findings by recording sympathetic skin responses from the neck area, which was not studied before.
A total of 37 unilateral patients with migraine (30 women, seven men) who fulfilled the criteria of International Headache Society (2004) were recruited from our outpatient clinic. The control group consisted of 21 healthy individuals (16 women, five men) who are employees or students of our Medical Faculty. Mean latency and maximum amplitude values of sympathetic skin responses obtained from neck areas of the patients during attack, post attack, and interval periods were calculated. We compared the mean latency and the maximum amplitude values of the symptomatic side with the data of the asymptomatic side and with the data of the control group. We also compared the responses of the patients with right-sided headache with the responses of the patients with left-sided headache. All statistical analyses were performed using SPSS.
On the neck area, we observed sympathetic hypo-function in the attack and interval periods and a relative hyper-function in the post attack period bilaterally, regardless of the symptomatic side.
These findings suggest that there is ongoing bilateral sympathetic hypo-function in the neck area and there occurs a temporary increase in the function of sympathetic sudomotor activity in the recovery period of headaches.
在本研究中，旨在评估单侧偏头痛患者和正常对照者在发作期、发作后期及间歇期的交感神经功能，并通过记录此前未被研究过的颈部区域的交感神经皮肤反应来比较这些结果。
从我们的门诊招募了37例符合国际头痛协会（2004年）标准的单侧偏头痛患者（30名女性，7名男性）。对照组由21名健康个体（16名女性，5名男性）组成，他们是我们医学院的员工或学生。计算患者在发作期、发作后期及间歇期从颈部区域获得的交感神经皮肤反应的平均潜伏期和最大振幅值。我们将有症状一侧的平均潜伏期和最大振幅值与无症状一侧的数据以及对照组的数据进行比较。我们还比较了右侧头痛患者与左侧头痛患者的反应。所有统计分析均使用SPSS进行。
在颈部区域，无论有症状的一侧如何，我们在发作期和间歇期观察到双侧交感神经功能减退，在发作后期观察到相对的功能亢进。
这些结果表明，颈部区域存在持续的双侧交感神经功能减退，并且在头痛恢复期交感神经汗腺运动活动功能会出现暂时增加。
