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小鼠中催乳素/生长激素基因家族的染色体定位

Chromosomal mapping of the prolactin/growth hormone gene family in the mouse.

作者信息

Jackson-Grusby L L, Pravtcheva D, Ruddle F H, Linzer D I

机构信息

Department of Biochemistry, Northwestern University, Evanston, Illinois 60208.

出版信息

Endocrinology. 1988 Jun;122(6):2462-6. doi: 10.1210/endo-122-6-2462.

DOI:10.1210/endo-122-6-2462
PMID:2836164
Abstract

The chromosomal assignments of genes in the PRL/GH family in the mouse have been determine in mouse-hamster hybrid cell lines. Mouse GH (mGH) appears to be encoded by a single copy gene located on chromosome 11 and is part of a highly conserved region between mouse chromosome 11 and human chromosome 17. All of the other genes in this hormone family, including those encoding mPRL, mouse placental lactogens I and II, and mouse proliferin and proliferin-related protein, map to chromosome 13.

摘要

已在小鼠 - 仓鼠杂交细胞系中确定了小鼠PRL/GH家族中基因的染色体定位。小鼠生长激素(mGH)似乎由位于11号染色体上的单拷贝基因编码,并且是小鼠11号染色体和人类17号染色体之间高度保守区域的一部分。该激素家族中的所有其他基因,包括编码mPRL、小鼠胎盘催乳素I和II以及小鼠增殖蛋白和增殖蛋白相关蛋白的基因,都定位于13号染色体。

相似文献

1
Chromosomal mapping of the prolactin/growth hormone gene family in the mouse.小鼠中催乳素/生长激素基因家族的染色体定位
Endocrinology. 1988 Jun;122(6):2462-6. doi: 10.1210/endo-122-6-2462.
2
Identification, characterization, and expression of a new prolactin-like molecule in the hamster placenta.仓鼠胎盘中一种新的催乳素样分子的鉴定、特性分析及表达
Biol Reprod. 1996 Aug;55(2):370-8. doi: 10.1095/biolreprod55.2.370.
3
The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21 to qter.生长激素基因和绒毛膜生长催乳素基因位于人类第17号染色体长臂的q21至qter区域。
Hum Genet. 1981;57(2):138-41. doi: 10.1007/BF00282009.
4
Characterization of a mouse mitogen-regulated protein/proliferin gene and its promoter: a member of the growth hormone/prolactin gene superfamily.小鼠促有丝分裂调节蛋白/增殖蛋白基因及其启动子的特性:生长激素/催乳素基因超家族的一个成员。
Biochim Biophys Acta. 1989 Sep 21;1009(1):75-82. doi: 10.1016/0167-4781(89)90081-x.
5
The prolactin gene is located on chromosome 6 in humans.催乳素基因位于人类的6号染色体上。
Science. 1981 May 15;212(4496):815-6. doi: 10.1126/science.7221563.
6
The mouse prolactin gene family locus.小鼠催乳素基因家族基因座。
Endocrinology. 2003 Jan;144(1):313-25. doi: 10.1210/en.2002-220724.
7
Chromosomal localization of the human placental lactogen-growth hormone gene cluster to 17q22-24.人胎盘催乳素-生长激素基因簇在染色体上定位于17q22 - 24。
Am J Hum Genet. 1982 Mar;34(2):227-34.
8
Sequence and expression of hamster prolactin and growth hormone messenger RNAs.
Endocrinology. 1991 Dec;129(6):2965-71. doi: 10.1210/endo-129-6-2965.
9
Pituitary-specific factor binding to the human prolactin, growth hormone, and placental lactogen genes.
DNA. 1989 Apr;8(3):149-59. doi: 10.1089/dna.1.1989.8.149.
10
Hamster placental lactogen-II contains a structural feature unique among the growth hormone-prolactin-placental lactogen family.
Mol Endocrinol. 1989 Nov;3(11):1710-3. doi: 10.1210/mend-3-11-1710.

引用本文的文献

1
STAT5 and prolactin participate in a positive autocrine feedback loop that promotes angiogenesis.STAT5 和催乳素参与促进血管生成的正自分泌反馈回路。
J Biol Chem. 2013 Jul 19;288(29):21184-21196. doi: 10.1074/jbc.M113.481119. Epub 2013 Jun 2.
2
Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus.23个小鼠催乳素/胎盘催乳素相关基因的时空表达与其在基因座中的位置无关。
BMC Genomics. 2008 Jul 28;9:352. doi: 10.1186/1471-2164-9-352.
3
Organization and evolution of a gene-rich region of the mouse genome: a 12.7-Mb region deleted in the Del(13)Svea36H mouse.
小鼠基因组富含基因区域的组织与进化:Del(13)Svea36H小鼠中缺失的一个12.7兆碱基区域
Genome Res. 2004 Oct;14(10A):1888-901. doi: 10.1101/gr.2478604. Epub 2004 Sep 13.
4
The prolactin and growth hormone families: pregnancy-specific hormones/cytokines at the maternal-fetal interface.催乳素和生长激素家族:母胎界面处的妊娠特异性激素/细胞因子。
Reprod Biol Endocrinol. 2004 Jul 5;2:51. doi: 10.1186/1477-7827-2-51.
5
Comparative map for mice and humans.小鼠与人类的比较图谱。
Mamm Genome. 1991;1 Spec No:S461-515. doi: 10.1007/BF00656504.
6
Mouse chromosome 13.小鼠13号染色体。
Mamm Genome. 1991;1 Spec No:S205-20. doi: 10.1007/BF00656494.
7
Mouse chromosome 11.小鼠11号染色体。
Mamm Genome. 1991;1 Spec No:S158-91. doi: 10.1007/BF00656492.
8
Placental-specific expression from the mouse placental lactogen II gene promoter.
Proc Natl Acad Sci U S A. 1992 May 1;89(9):3864-8. doi: 10.1073/pnas.89.9.3864.
9
Mouse chromosome 13.小鼠13号染色体。
Mamm Genome. 1992;3 Spec No:S195-205. doi: 10.1007/BF00648431.
10
Mouse chromosome 11.小鼠11号染色体。
Mamm Genome. 1992;3 Spec No:S162-81. doi: 10.1007/BF00648429.