DeKoven Samuel, DeKoven Joel, Holness D Linn
1 Doctor of Medicine Program, Schulich School of Medicine and Dentistry, London, ON, Canada.
2 Division of Occupational Medicine, Department of Medicine, St Michael's Hospital, Toronto, ON, Canada.
J Cutan Med Surg. 2017 Jul/Aug;21(4):340-344. doi: 10.1177/1203475417701420. Epub 2017 Mar 31.
Recently, many cases of acrylate-associated allergic contact dermatitis have appeared among nail salon workers. Common acrylate-containing products in nail salons include traditional nail polish, ultraviolet-cured shellac nail polish, ultraviolet-cured gel nails, and press-on acrylic nails.
Nail salon technicians seen in the occupational medicine clinic in 2015 and 2016 were identified, and their patch test results and clinical features were summarized. Patch testing was done with the Chemotechnique (Meth)Acrylate nail series, and either the North American Standard series or the North American Contact Dermatitis Group screening series.
Six patients were identified, all women, ages 38 to 58. Common presentations included erythematous dermatitis of the dorsa of the hands, palms, and forearms and fissures on the fingertips. Less common sites of eruptions included the periorbital region, cheeks, posterior ears, neck, sacral area, lateral thighs, and dorsa of the feet. All patients reacted to hydroxyethyl methacrylate, and 5 patients reacted to ethyl acrylate. Each patient also reacted to (meth)acrylates that are not found on either standard series, including ethyleneglycol dimethacrylate, 2-hydroxypropyl methacrylate, and 2-hydroxyethyl acrylate.
The authors report 6 cases of allergic contact dermatitis to acrylates in nail technicians seen over the past year, representing a new trend in their clinic. These cases are reflective of a growing trend of nail technicians with allergic contact dermatitis associated with occupational (meth)acrylate exposure. Efforts to improve prevention are needed.
最近，美甲沙龙工作人员中出现了许多与丙烯酸酯相关的过敏性接触性皮炎病例。美甲沙龙中常见的含丙烯酸酯产品包括传统指甲油、紫外线固化甲油胶、紫外线固化凝胶甲以及贴片式丙烯酸指甲。
确定了2015年和2016年在职业医学诊所就诊的美甲沙龙技术人员，并总结了他们的斑贴试验结果和临床特征。使用Chemotechnique（甲基）丙烯酸酯指甲系列以及北美标准系列或北美接触性皮炎小组筛查系列进行斑贴试验。
共确定6例患者，均为女性，年龄在38至58岁之间。常见表现包括手背、手掌和前臂的红斑性皮炎以及指尖皲裂。较少见的发疹部位包括眶周区域、脸颊、耳后、颈部、骶部、大腿外侧和足背。所有患者对甲基丙烯酸羟乙酯均有反应，5例患者对丙烯酸乙酯有反应。每位患者对两种标准系列中均未发现的（甲基）丙烯酸酯也有反应，包括乙二醇二甲基丙烯酸酯、甲基丙烯酸2-羟丙酯和丙烯酸2-羟乙酯。
作者报告了过去一年中在美甲技术人员中发现的6例对丙烯酸酯的过敏性接触性皮炎病例，这在他们的诊所中代表了一种新趋势。这些病例反映了美甲技术人员中与职业性（甲基）丙烯酸酯暴露相关的过敏性接触性皮炎呈增长趋势。需要努力改进预防措施。
