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Radial dose distributions from carbon ions of therapeutic energies calculated with Geant4-DNA.

作者信息

Wang He, Vassiliev Oleg N

机构信息

Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, United States of America.

出版信息

Phys Med Biol. 2017 May 21;62(10):N219-N227. doi: 10.1088/1361-6560/aa6a90. Epub 2017 Mar 31.

DOI:10.1088/1361-6560/aa6a90
PMID:28362271
Abstract

We report on radial dose distributions [Formula: see text] for carbon ions calculated with Geant4-DNA code. These distributions characterize ion tracks on a nanoscale and are important for understanding the biological effects of ion beams. We present data for carbon ion beams in the energy range from 20 to 400 MeV u. To approximate the Monte Carlo results, we developed a simple formula that combines the well-known inverse square distance dependence with a factor correcting [Formula: see text] for small [Formula: see text]. The proposed formula can be used to calculate [Formula: see text] for any energy within the above range and for distances [Formula: see text] from 1 nm to 2 μm with a maximum error not exceeding 14%. This range of distances corresponds to a dose range of over seven orders of magnitude. Differences between our results and those of previously published analytical models are discussed.

摘要

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