Viale G, Doglioni C, Iuzzolino P, Bontempini L, Colombi R, Coggi G, Dell'Orto P
Second Department of Pathology, University of Milan School of Medicine, Italy.
Histopathology. 1988 Apr;12(4):415-24. doi: 10.1111/j.1365-2559.1988.tb01956.x.
Two adult cases of a cutaneous lesion indistinguishable from typical infantile digital fibromatosis are added to the unique similar case so far reported in adulthood. The immunocytochemical localization of vimentin and muscle actin in the proliferating cells confirms their myofibroblastic nature and establishes closer relationships between the adult and the infantile variants of this entity. These two variants, however, appear to be clinically different, since all the adult cases were extradigital and did not recur after surgical excision. The term inclusion body fibromatosis underlines the histological hallmark of the lesion and should be used to identify this entity in place of recurrent infantile digital fibromatosis which does not seem any longer appropriate.
两例成年皮肤病变病例，其表现与典型婴儿指部纤维瘤病难以区分，这被纳入到迄今为止报道的成年期独特类似病例中。波形蛋白和肌动蛋白在增殖细胞中的免疫细胞化学定位证实了它们的肌成纤维细胞性质，并在该实体的成年和婴儿变体之间建立了更紧密的关系。然而，这两种变体在临床上似乎有所不同，因为所有成年病例均发生于指外，手术切除后未复发。包涵体纤维瘤病这一术语强调了病变的组织学特征，应以此来识别该实体，而不再适用复发性婴儿指部纤维瘤病这一名称。
