Canioni D, Richard S, Rambaud C, Manach Y, Nezelof C
Groupe de Pathologie Pédiatrique, Hôpital des Enfants Malades, Paris, France.
Pathol Res Pract. 1991 Sep;187(7):886-9; discussion 889-91. doi: 10.1016/s0344-0338(11)80586-8.
This report illustrates a lingual localization of an inclusion body fibromatosis, the so-called Reye tumor or infantile digital fibromatosis (IDF). The light microscopic features were identical to those found in IDF, showing eosinophilic perinuclear inclusions located in spindle-shaped cells arranged in interlacing fascicles. The immunocytochemical and ultrastructural findings suggested a fibroblastic and/or myofibroblastic nature of the proliferative cells. However, the inclusions in our case were strongly stained with vimentin and their ultrastructural appearance was in keeping with intermediate filaments. These findings have never been described in other reports of fibromatosis. Whereas most reviews state that IDF occurs exclusively on the digits, this unique case describes its possible occurrence in the tongue.
本报告阐述了一例包涵体纤维瘤病的舌部定位，即所谓的雷伊肿瘤或婴儿指部纤维瘤病（IDF）。光镜下特征与IDF所见相同，显示嗜酸性核周包涵体位于交织束状排列的梭形细胞中。免疫细胞化学和超微结构检查结果提示增殖细胞具有成纤维细胞和/或肌成纤维细胞性质。然而，我们病例中的包涵体波形蛋白染色呈强阳性，其超微结构外观与中间丝相符。这些发现从未在其他纤维瘤病报告中描述过。尽管大多数综述称IDF仅发生于手指，但本独特病例描述了其可能发生于舌部。
