基于人群的中风和痴呆发病率趋势：年龄和性别差异。
Population-based stroke and dementia incidence trends: Age and sex variations.
机构信息
Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.
Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada; Ivey Business School, Western University, London, Ontario, Canada.
出版信息
Alzheimers Dement. 2017 Oct;13(10):1081-1088. doi: 10.1016/j.jalz.2017.02.010. Epub 2017 Mar 28.
INTRODUCTION
We discovered a concomitant decline in stroke and dementia incidence rates at a whole population level in Ontario, Canada. This study explores these trends within demographic subgroups.
METHODS
We analyzed administrative data sources using validated algorithms to calculate stroke and dementia incidence rates from 2002 to 2013.
RESULTS
For more than 12 years, stroke incidence remained unchanged among those aged 20 to 49 years and decreased for those aged 50 to 64, 65 to 79, and 80+ years by 22.7%, 36.9%, and 37.9%, respectively. Dementia incidence increased by 17.3% and 23.5% in those aged 20 to 49 and 50 to 64 years, respectively, remained unchanged in those aged 65 to 79 years, and decreased by 15.4% in those aged 80+ years.
DISCUSSION
The concomitant decline in stroke and dementia incidence rates may depict how successful stroke prevention has targeted shared risk factors of both conditions, especially at advanced ages where such risk factors are highly prevalent. We lend support for the development of an integrated system of stroke and dementia prevention.
简介
我们在加拿大安大略省的整个人群水平上发现了中风和痴呆发病率的同时下降。本研究探讨了这些趋势在人口统计学亚组中的表现。
方法
我们使用经过验证的算法分析了行政数据源，以计算 2002 年至 2013 年的中风和痴呆发病率。
结果
12 多年来，20 至 49 岁人群的中风发病率保持不变，50 至 64 岁、65 至 79 岁和 80 岁以上人群的中风发病率分别下降了 22.7%、36.9%和 37.9%。20 至 49 岁和 50 至 64 岁人群的痴呆发病率分别增加了 17.3%和 23.5%，65 至 79 岁人群的痴呆发病率保持不变，80 岁以上人群的痴呆发病率下降了 15.4%。
讨论
中风和痴呆发病率的同时下降可能表明中风预防措施针对这两种疾病的共同风险因素取得了成功，特别是在这些风险因素高度流行的高年龄段。我们支持建立一个综合的中风和痴呆预防系统。
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