Lanuti Michael
Division of Thoracic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Founders 7, Boston, MA 02114, USA.
Thorac Surg Clin. 2017 May;27(2):195-199. doi: 10.1016/j.thorsurg.2017.01.013.
The prevalence of chest wall invasion by non-small cell lung cancer is < 10% in published surgical series. The role of radiation or chemotherapy around the complete resection of lung cancer invading the chest wall, excluding the superior sulcus of the chest, is poorly defined. Survival of patients with lung cancer invading the chest wall is dependent on lymph node involvement and completeness of en-bloc resection. In some patients harboring T3N0 disease, 5-year survival in excess of 50% can be achieved. Offering en-bloc resection of lung cancer invading chest wall to patients with T3N1 or T3N2 disease is controversial.
在已发表的外科手术系列研究中,非小细胞肺癌侵犯胸壁的发生率<10%。对于侵犯胸壁(不包括胸廓上沟)的肺癌,在完整切除肿瘤周围进行放疗或化疗的作用尚不明确。肺癌侵犯胸壁患者的生存率取决于淋巴结受累情况及整块切除的完整性。对于一些患有T3N0疾病的患者,5年生存率可超过50%。对于T3N1或T3N2疾病的患者,是否提供肺癌侵犯胸壁的整块切除存在争议。