Surface Engineering and Tribology Division, CSIR-Central Mechanical Engineering Research Institute, Mahatma Gandhi Avenue, Durgapur 713209, District: Burdwan, West Bengal, India.
Surface Engineering and Tribology Division, CSIR-Central Mechanical Engineering Research Institute, Mahatma Gandhi Avenue, Durgapur 713209, District: Burdwan, West Bengal, India.
Anal Chim Acta. 2017 May 1;965:111-122. doi: 10.1016/j.aca.2017.02.008. Epub 2017 Feb 20.
Schiff base organic compound (SOC) has been prepared as a tritopic chemosensor for selective sensing by fluorescence signalling towards ions like Al, F and explosive molecule like TNP. In general, fluorescence like photophysical property has been used for selective detection of analyte where Al and F show turn-on fluorescence signal at different wavelengths (nm) however, quenching was found with TNP. As a consequence, the chemosensor has become a selective sensor for Al, F and TNP. Reversibility of fluorescence responses for Al and F are observed in presence of ammonium nitrate and H respectively. Similar to the detection of TNP, the detection of explosive like NO salts is also essential from homeland security point of view. In the present work, the finding of reversible sequential fluorescence response can be promoted for fabrication of next generation AND-NOT-OR-NAND-XOR-XNOR-NOR based complex logic circuit which is applicable in photonics, security and other fields including inorganic and material science. In the case of TNP recognition, the pathway mainly depends on non-covalent interaction (quenching constant: 4.4 × 10 M) which is even better than the recently reported materials. Detection limit for Al, F and TNP is 1 μM, 3 μM and 500 nM respectively. DFT-D3 has been carried out to explore the host⋯guest interaction along with the structure-property correlation of the present host-guest system. All three guest analytes have been detected inside the living cell at a certain level and in its consequence, the successful in vitro recognition ability of the SOCs inside human cell line HeLa has been explored too. In real time stepping, an easy to operate and an economically affordable pocket prototype has also been fabricated for on spot detection of TNP like explosive.
席夫碱有机化合物（SOC）已被制备为三齿化学传感器，通过荧光信号对离子如 Al、F 和爆炸分子如 TNP 进行选择性传感。一般来说，荧光等光物理性质已被用于选择性检测分析物，其中 Al 和 F 在不同波长（nm）下显示出开启荧光信号，而 TNP 则显示出猝灭。因此，该化学传感器成为 Al、F 和 TNP 的选择性传感器。在存在硝酸铵和 H 的情况下，观察到 Al 和 F 的荧光响应的可逆性。与 TNP 的检测类似，从国土安全的角度来看，对类似爆炸物的硝酸盐的检测也是必不可少的。在目前的工作中，发现可逆顺序荧光响应可以促进下一代基于 AND-NOT-OR-NAND-XOR-XNOR-NOR 的复杂逻辑电路的制造，该电路可应用于光子学、安全和其他领域，包括无机和材料科学。在 TNP 识别的情况下，途径主要取决于非共价相互作用（猝灭常数：4.4×10 M），甚至优于最近报道的材料。Al、F 和 TNP 的检测限分别为 1 μM、3 μM 和 500 nM。已经进行了 DFT-D3 以探索主体⋯客体相互作用以及本主体-客体系统的结构-性质相关性。所有三种客体分析物都在一定水平上在活细胞内被检测到，并且在其结果中，还探索了 SOCs 在人宫颈癌细胞系 HeLa 内的成功体外识别能力。在实时逐步中，还制造了一种易于操作且经济实惠的口袋原型，用于现场检测类似 TNP 的爆炸物。
