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Pharmacol Ther. 2017 Feb;170:64-72. doi: 10.1016/j.pharmthera.2016.10.011. Epub 2016 Oct 20.
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Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.替莫唑胺化疗与放疗治疗高危低级别胶质瘤的对比研究(欧洲癌症研究与治疗组织22033-26033):一项随机、开放标签的3期组间研究。
Lancet Oncol. 2016 Nov;17(11):1521-1532. doi: 10.1016/S1470-2045(16)30313-8. Epub 2016 Sep 27.
4
Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.高危低级别胶质瘤患者的健康相关生活质量(EORTC 22033-26033):一项随机、开放标签、III 期分组间研究。
Lancet Oncol. 2016 Nov;17(11):1533-1542. doi: 10.1016/S1470-2045(16)30305-9. Epub 2016 Sep 27.
5
Practical implications of integrated glioma classification according to the World Health Organization classification of tumors of the central nervous system 2016.根据2016年世界卫生组织中枢神经系统肿瘤分类进行的综合胶质瘤分类的实际意义。
Curr Opin Oncol. 2016 Nov;28(6):494-501. doi: 10.1097/CCO.0000000000000327.
6
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.2016 年世界卫生组织中枢神经系统肿瘤分类:概述。
Acta Neuropathol. 2016 Jun;131(6):803-20. doi: 10.1007/s00401-016-1545-1. Epub 2016 May 9.
7
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过去10年的里程碑:中枢神经系统癌症。

Milestones of the last 10 years: CNS cancer.

作者信息

Marosi Christine, Preusser Matthias

机构信息

Division of Oncology, Department of Medicine I, Medical University Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

出版信息

Memo. 2017;10(1):18-21. doi: 10.1007/s12254-016-0309-x. Epub 2017 Jan 25.

DOI:10.1007/s12254-016-0309-x
PMID:28367251
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5357257/
Abstract

For neuro-oncologists, much was accomplished in the last decade, including the establishment of the first standard of care (SOC) in this field of oncology. New treatment options boosted research in the whole field of neuro-oncology, as well clinical trials, translational and basic research. Accumulated data on molecular-genetic subgroups with distinct clinical outcomes in disease entities led to the establishment of new biomarkers and to the collaborative formulation of a new WHO classification of central nervous system tumors.

摘要

对于神经肿瘤学家而言,过去十年取得了诸多成就,包括在该肿瘤学领域确立了首个标准治疗方案(SOC)。新的治疗选择推动了神经肿瘤学整个领域的研究,以及临床试验、转化研究和基础研究。关于疾病实体中具有不同临床结果的分子遗传亚组的累积数据,促成了新生物标志物的建立以及世界卫生组织(WHO)中枢神经系统肿瘤新分类的协同制定。