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腺性新发精神病:甲状腺危象背景下伴有自杀观念和自杀未遂的成人新发精神病

Gland New Psychosis: New Onset Adult Psychosis with Suicidal Ideation and Attempt in the Setting of Thyroid Storm.

作者信息

Cota Esteban, Lentz Jacob

机构信息

David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095, USA.

UCLA Medical Center, 757 Westwood Blvd, Los Angeles, CA 90095, USA.

出版信息

Case Rep Psychiatry. 2017;2017:7402923. doi: 10.1155/2017/7402923. Epub 2017 Mar 7.

Abstract

We present a case of new onset psychosis in the setting of thyroid storm in a woman with no previous psychiatric history. The patient presented with ongoing suicidal ideation, a suicide attempt that was interrupted by her husband, and audio and visual hallucinations. The patient was placed on a psychiatric hold and treated for thyrotoxicosis as well as psychosis. Treatment of the thyroid hormone overload resulted in a rapid resolution of her symptoms; she was discharged in excellent condition, and she has had no repeat hallucinations or self-injury ideation or attempts since. Although rare, thyrotoxicosis is a potentially life-threatening cause of psychiatric illness and should always be kept on the differential diagnosis for a patient with a first episode of psychosis. This case highlights how thyroid storm physiology, beyond its well-studied hemodynamic and metabolic instability, can be potentially fatal due to psychiatric sequelae. It also highlights the crucial role of a thorough history and physical exam in all patients.

摘要

我们报告一例既往无精神病史的女性在甲状腺危象时出现新发精神病的病例。患者表现为持续的自杀意念、一次被其丈夫打断的自杀未遂行为以及视听幻觉。患者被实施精神科约束并接受甲状腺毒症及精神病的治疗。甲状腺激素负荷过重的治疗使她的症状迅速缓解;她出院时状况良好,自那以后未再出现幻觉、自我伤害意念或企图。尽管罕见,但甲状腺毒症是一种潜在危及生命的精神疾病病因,对于首次发作精神病的患者应始终将其列入鉴别诊断。该病例突出表明,甲状腺危象的生理状态,除了其已得到充分研究的血流动力学和代谢不稳定之外,由于精神科后遗症可能具有潜在致命性。它还突出了全面病史和体格检查在所有患者中的关键作用。

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本文引用的文献

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Endocrine and metabolic emergencies: thyroid storm.内分泌和代谢急症:甲状腺危象。
Ther Adv Endocrinol Metab. 2010 Jun;1(3):139-45. doi: 10.1177/2042018810382481.
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Thyrotoxicosis.甲状腺功能亢进症。
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