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射波刀立体定向体部放射治疗胸腺肿瘤

Thymic Carcinoma Treated by CyberKnife Stereotactic Body Radiotherapy.

作者信息

Harada Yuko, Miyazaki Shinichiro

机构信息

Internal Medicine, Shin-yurigaoka General Hospital.

Radiation Oncology, Shin-yurigaoka General Hospital.

出版信息

Cureus. 2017 Feb 26;9(2):e1056. doi: 10.7759/cureus.1056.

DOI:10.7759/cureus.1056
PMID:28367393
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5364086/
Abstract

The standard treatment for advanced thymic carcinoma has not yet been established. Most patients have no symptoms until the advanced stage. Radiation therapy has been used for advanced stage cancer, usually in combination with surgery or chemotherapy; however, the survival rates are 30%-50%. We performed hypofractionated stereotactic radiotherapy with CyberKnife (Accuray, Sunnyvale, CA, USA) for 10 cases of advanced thymic cancer. All cases reached at least partial remission (PR) in two months with progression-free irradiated lesions and minimal radiation-related toxicity. It took only seven to 12 days for each therapy that did not require admission. CyberKnife is beneficial for patients even at the terminal stage.

摘要

晚期胸腺癌的标准治疗方法尚未确立。大多数患者直到晚期才出现症状。放射治疗已用于晚期癌症,通常与手术或化疗联合使用;然而,生存率为30%-50%。我们使用射波刀(美国加利福尼亚州森尼韦尔市Accuray公司生产)对10例晚期胸腺癌患者进行了大分割立体定向放射治疗。所有病例在两个月内均至少达到部分缓解(PR),照射部位无疾病进展,且与放疗相关的毒性极小。每次治疗仅需7至12天,无需住院。即使对于晚期患者,射波刀也是有益的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5334/5364086/8fae56c98f00/cureus-0009-00000001056-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5334/5364086/2f8ebb09cd84/cureus-0009-00000001056-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5334/5364086/8fae56c98f00/cureus-0009-00000001056-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5334/5364086/2f8ebb09cd84/cureus-0009-00000001056-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5334/5364086/8fae56c98f00/cureus-0009-00000001056-i02.jpg

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引用本文的文献

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Sci Rep. 2017 Oct 19;7(1):13549. doi: 10.1038/s41598-017-12909-z.

本文引用的文献

1
Thymoma and thymic carcinomas.胸腺瘤和胸腺癌。
Crit Rev Oncol Hematol. 2016 Mar;99:332-50. doi: 10.1016/j.critrevonc.2016.01.012. Epub 2016 Jan 19.
2
Stereotactic ablative radiotherapy with CyberKnife for advanced thymic carcinoma: a case report.射波刀立体定向消融放疗治疗晚期胸腺癌:病例报告
Curr Oncol. 2015 Oct;22(5):e391-4. doi: 10.3747/co.22.2693.
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Radiotherapy for thymic carcinoma: adjuvant, inductive, and definitive.胸腺癌的放射治疗:辅助性、诱导性和根治性。
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Thymoma and thymic carcinoma.胸腺瘤和胸腺癌。
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Thymic carcinoma: state of the art review.胸腺癌:最新综述
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Thymic tumors.胸腺瘤
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Int J Cancer. 2003 Jul 1;105(4):546-51. doi: 10.1002/ijc.11099.
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