阳离子钴催化的 O-(烷氧羰基)-N-芳基羟胺的[1,3]-重排反应。
Concerted [1,3]-Rearrangement in Cationic Cobalt-Catalyzed Reaction of O-(Alkoxycarbonyl)-N-arylhydroxylamines.
机构信息
Research and Analytical Center for Giant Molecules and ‡Department of Chemistry, Graduate School of Science, Tohoku University , Sendai 980-8578, Miyagi, Japan.
出版信息
Org Lett. 2017 Apr 21;19(8):2194-2196. doi: 10.1021/acs.orglett.7b00700. Epub 2017 Apr 3.
PMID:28368604
Abstract
O-(Alkoxycarbonyl)-N-arylhydroxylamines were efficiently converted to 2-aminophenol derivatives by cationic cobalt catalysts at 30 °C. The results of O-labeling experiments suggested that rearrangement of the alkoxycarbonyl group from the aniline nitrogen to the ortho position proceeded in an unprecedented [1,3] manner.
摘要
O-(烷氧基羰基)-N-芳基羟胺在 30°C 下被阳离子钴催化剂有效地转化为 2-氨基酚衍生物。O 标记实验的结果表明，烷氧基羰基基团从未有过的[1,3]方式从苯胺氮原子重排到邻位。
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