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门诊 5-13 岁儿童人偏肺病毒感染的临床特征。

Clinical Features of Human Metapneumovirus Infection in Ambulatory Children Aged 5-13 Years.

机构信息

Vanderbilt University Medical Center, Nashville, Tennessee.

University of Rochester School of Medicine and Dentistry, New York.

出版信息

J Pediatric Infect Dis Soc. 2018 May 15;7(2):165-168. doi: 10.1093/jpids/pix012.

DOI:10.1093/jpids/pix012
PMID:28369564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5954304/
Abstract

We detected human metapneumovirus (HMPV) in 54 (5%) of 1055 children aged 5 to 13 years with acute respiratory illness (ARI) identified by outpatient and emergency department surveillance between November and May 2003-2009. Its clinical features were similar to those of HMPV-negative ARI, except a diagnosis of pneumonia was more likely (13% vs 4%, respectively; P = .005) and a diagnosis of pharyngitis (7% vs 24%, respectively; P = .005) was less likely in patients with HMPV- positive ARI than those with HMPV-negative ARI.

摘要

我们在 2003 年至 2009 年 11 月至 5 月间通过门诊和急诊部门监测发现,在 5 至 13 岁患有急性呼吸道疾病(ARI)的 1055 名儿童中,有 54 名(5%)检测出人类偏肺病毒(HMPV)呈阳性。除了肺炎的诊断(分别为 13%和 4%;P =.005)更有可能外,HMPV 阳性 ARI 患者的咽炎诊断(分别为 7%和 24%;P =.005)比 HMPV 阴性 ARI 患者更少。

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本文引用的文献

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Incidence, Morbidity, and Costs of Human Metapneumovirus Infection in Hospitalized Children.住院儿童人偏肺病毒感染的发病率、患病率及费用
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Community-acquired pneumonia requiring hospitalization among U.S. children.美国儿童中需要住院治疗的社区获得性肺炎。
N Engl J Med. 2015 Feb 26;372(9):835-45. doi: 10.1056/NEJMoa1405870.
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Burden of human metapneumovirus infection in young children.人偏肺病毒感染在幼儿中的负担。
N Engl J Med. 2013 Feb 14;368(7):633-43. doi: 10.1056/NEJMoa1204630.
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Real-time reverse transcriptase PCR assay for improved detection of human metapneumovirus.实时逆转录聚合酶链反应检测法提高了对人类偏肺病毒的检测。
J Clin Virol. 2012 Aug;54(4):371-5. doi: 10.1016/j.jcv.2012.05.005. Epub 2012 Jun 6.
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Coronavirus infection and hospitalizations for acute respiratory illness in young children.幼儿的冠状病毒感染及急性呼吸道疾病住院情况。
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Parainfluenza virus infection of young children: estimates of the population-based burden of hospitalization.幼儿副流感病毒感染:基于人群的住院负担估计
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