Beckett Megan K, Elliott Marc N, Ritenour Douglas, Giordano Laura A, Grace Susan C, Malinoff Rochelle, Saliba Debra
RAND, Santa Monica, California.
Health Services Advisory Group, Phoenix, Arizona.
J Am Geriatr Soc. 2017 May;65(5):1051-1055. doi: 10.1111/jgs.14734. Epub 2017 Apr 3.
To use items from the Medicare Health Outcomes Survey (HOS) to adapt or validate a simple method for identifying community-dwelling older adults at greater risk of death and to extend the method to identify a very high-risk group.
Analysis of longitudinal data.
National sample of beneficiaries from Medicare Advantage plans with 500 or more enrollees.
Medicare beneficiaries aged 65 and older responding to 2009 baseline and 2011 follow-up HOS (N = 238,687).
Bivariate and multivariate analyses of the HOS; adaptation and validation of a previously validated Vulnerable Elders Survey-13 (VES-13) scoring system that uses age and self-reported function to predict mortality.
A modified predictive model, that uses substitutes for several items in the previously validated VES-13, predicted 2-year mortality; 10.6% of those scoring 3 or more, and 2.4% of those scoring less than 3 died within 2 years (relative risk of death 4.4, similar to 4.2 for the original VES-13 sample), and 15.5% of those scoring 7 or more died within 2 years (relative risk of death (relative to scores <3) of 6.5). Sixteen percent of HOS beneficiaries were missing some data; 2-year mortality for those with missing items was 9.5%, versus 7.1% for those with no missing items (P < .001). Imputation of median values for missing VES-13 items results in valid predictions of mortality for those with partially missing data.
The VES-13 algorithm is robust to substitution of functional items and can be used to identify very high-risk older adults. Multiple imputation of missing items reduces loss-to-follow-up bias and increases sample size.
运用医疗保险健康结果调查(HOS)中的项目来调整或验证一种识别社区居住的死亡风险较高的老年人的简单方法,并扩展该方法以识别极高风险组。
纵向数据分析。
来自参保人数达500人或更多的医疗保险优势计划受益人的全国样本。
年龄在65岁及以上的医疗保险受益人,他们对2009年基线和2011年随访HOS进行了回应(N = 238,687)。
对HOS进行双变量和多变量分析;调整并验证先前验证过的脆弱老年人调查-13(VES-13)评分系统,该系统使用年龄和自我报告功能来预测死亡率。
一种经过修改的预测模型,使用先前验证过的VES-13中几个项目的替代指标,可预测2年死亡率;得分3分及以上者中有10.6%,得分低于3分者中有2.4%在2年内死亡(死亡相对风险为4.4,与原始VES-13样本的4.2相似),得分7分及以上者中有15.5%在2年内死亡(相对于得分<3者的死亡相对风险为6.5)。16%的HOS受益人缺失一些数据;有缺失项目者的2年死亡率为9.5%,无缺失项目者为7.1%(P <.001)。对缺失的VES-13项目进行中位数插补可有效预测部分数据缺失者的死亡率。
VES-13算法对功能项目的替代具有稳健性,可用于识别极高风险的老年人。对缺失项目进行多重插补可减少失访偏倚并增加样本量。