Division of Geriatrics, University of California at Los Angeles, Los Angeles, California, USA.
J Am Geriatr Soc. 2009 Nov;57(11):2070-6. doi: 10.1111/j.1532-5415.2009.02497.x. Epub 2009 Sep 28.
To test the predictive properties of the Vulnerable Elders-13 Survey (VES-13) a short tool that predicts functional decline and mortality over a 1- to 2-year follow-up interval over a 5-year interval.
Longitudinal evaluation with mean follow-up of 4.5 years.
Two managed-care organizations.
Six hundred forty-nine community-dwelling older adults (> or = 75) enrolled in the Assessing Care of Vulnerable Elders observational study who screened positive for symptoms of falls or fear of falling, bothersome urinary incontinence, or memory problems.
VES-13 score (range 1-10, higher score indicates worse prognosis), functional decline (decline in count of 5 activities of daily living or nursing home entry), and deaths.
Higher VES-13 scores were associated with greater predicted probability of death and decline in older patients over a mean observation period of 4.5 years. For each additional VES-13 point, the odds of the combined outcome of functional decline or death was 1.37 (95% confidence interval (CI)=1.25-1.50), and the area under the receiver operating curve was 0.75 (95% CI=0.71-0.80). In the Cox proportional hazards model predicting time to death, the hazard ratio was 1.23 (95% CI=1.19-1.27) per additional VES-13 point.
This study extends the utility of the VES-13 to clinical decisions that require longer-term prognostic estimates of functional status and survival.
测试脆弱老年人 13 项调查(VES-13)的预测性能,这是一种短工具,可以在 5 年的随访间隔内预测 1 至 2 年的功能下降和死亡率。
具有 4.5 年平均随访时间的纵向评估。
两个管理式医疗组织。
649 名居住在社区的老年人(>或= 75 岁)参加了脆弱老年人评估观察研究,他们对跌倒或跌倒恐惧、令人烦恼的尿失禁或记忆问题的症状筛查呈阳性。
VES-13 评分(范围 1-10,分数越高表示预后越差)、功能下降(日常生活活动计数下降 5 项或进入疗养院)和死亡。
较高的 VES-13 评分与老年患者在平均 4.5 年的观察期内死亡和功能下降的预测概率增加相关。对于每个额外的 VES-13 点,功能下降或死亡的综合结果的几率为 1.37(95%置信区间(CI)=1.25-1.50),接收者操作曲线下的面积为 0.75(95%CI=0.71-0.80)。在预测死亡时间的 Cox 比例风险模型中,每增加一个 VES-13 点,风险比为 1.23(95%CI=1.19-1.27)。
本研究扩展了 VES-13 的用途,可用于需要对功能状态和生存进行更长期预后估计的临床决策。