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貉和蓝狐细小病毒的生物学及抗原特性鉴定:一项单克隆抗体研究

Characterization of biological and antigenic properties of raccoon dog and blue fox parvoviruses: a monoclonal antibody study.

作者信息

Veijalainen P

机构信息

National Veterinary Institute, Helsinki, Finland.

出版信息

Vet Microbiol. 1988 Mar;16(3):219-30. doi: 10.1016/0378-1135(88)90026-0.

DOI:10.1016/0378-1135(88)90026-0
PMID:2836994
Abstract

Parvovirus isolates from blue foxes and raccoon dogs were characterized by studying their haemagglutination properties, host range in vitro and antigenic structure. In all 3 characters, raccoon dog parvovirus resembled canine parvovirus (CPV), while blue fox parvovirus was similar to mink enteritis virus (MEV). Monoclonal antibodies (MAbs) were prepared against both viruses. Raccoon dog parvovirus, while resembling CPV, had a unique antigenic site which could be specified by MAbs. The pattern of MAbs prepared against blue fox parvovirus indicated that it is a member of Type 2 MEV.

摘要

通过研究蓝狐和貉细小病毒的血凝特性、体外宿主范围及抗原结构对其进行了特性鉴定。在所有这三个特征方面,貉细小病毒类似于犬细小病毒(CPV),而蓝狐细小病毒则与水貂肠炎病毒(MEV)相似。针对这两种病毒制备了单克隆抗体(MAb)。貉细小病毒虽然与CPV相似,但有一个独特的抗原位点,可由单克隆抗体加以确定。针对蓝狐细小病毒制备的单克隆抗体模式表明,它是2型水貂肠炎病毒的一个成员。

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The emergence of parvoviruses of carnivores.肉食动物细小病毒的出现。
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Feline host range of canine parvovirus: recent emergence of new antigenic types in cats.犬细小病毒的猫宿主范围:猫中新抗原型的近期出现
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There is nothing permanent except change. The emergence of new virus diseases.除了变化,没有什么是永恒的。新病毒疾病的出现。
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