Jacquet E, Chambert J, Pauchot J, Sandoz P
Department of Applied Mechanics, CNRS/UFC/ENSMM/UTBM, FEMTO-ST Institute, Univ. Bourgogne Franche-Comté, Besançon, France.
Service de Chirurgie Orthopédique, Traumatologique et Plastique, CHRU J. Minjoz, Univ. Bourgogne Franche-Comté, Centre Hospitalier Régional Universitaire, Besançon, France.
Skin Res Technol. 2017 Nov;23(4):491-499. doi: 10.1111/srt.12361. Epub 2017 Mar 30.
BACKGROUND/PURPOSE: The mechanical properties and behavior of the human skin in vivo are of medical importance, particularly to surgeons who have to consider the skin extension capabilities in the preparation of surgical acts. Variable data can be found in literature that result from diverse kinds of tests (in vivo, ex vivo, and postmortem) performed with different instruments.
This paper presents the results of in vivo measurements performed on a cohort of 20 healthy volunteers with an ultralight homemade uniaxial extensometer. Different anatomical zones were explored under different directions of solicitation in order to document inter- and intra-individual variability as well as skin anisotropy.
The experimental data obtained are fitted with a phenomenological exponential model allowing the identification of three parameters characteristic of the tested skin behavior. These parameters can be related to the concept of skin extensibility used by surgeons.
The inter- and intra-variability observed on that cohort confirms the need for a patient-specific approach based on the in vivo measurement of the mechanical behavior of the human skin of interest. Even the direction of higher skin stiffness is found to be individual-dependent. The capability of the extensometer used in this study to fulfill such measurement needs is also demonstrated.
背景/目的：人体皮肤在体内的力学性能和行为具有医学重要性，对于那些在手术操作准备过程中必须考虑皮肤伸展能力的外科医生来说尤为如此。文献中可找到因使用不同仪器进行的各种测试（体内、体外和死后）而产生的不同数据。
本文介绍了使用超轻型自制单轴拉伸仪对20名健康志愿者进行体内测量的结果。在不同的牵拉方向下探索不同的解剖区域，以记录个体间和个体内的变异性以及皮肤各向异性。
所获得的实验数据与一个唯象指数模型拟合，该模型可确定测试皮肤行为的三个特征参数。这些参数可与外科医生使用的皮肤伸展性概念相关联。
在该队列中观察到的个体间和个体内变异性证实了基于对感兴趣的人体皮肤力学行为进行体内测量的个体化方法的必要性。甚至发现皮肤刚度较高的方向也因人而异。本研究中使用的拉伸仪满足此类测量需求的能力也得到了证明。
