Uribe Flavio, Davoody Leyla, Mehr Rana, Jayaratne Yasas S N, Almas Khalid, Sobue Takanori, Allareddy Veerasathpurush, Nanda Ravindra
Division of Orthodontics, Department of Craniofacial Sciences, University of Connecticut School of Dental Medicine, Farmington, USA.
Department of Preventive Dental Science, University of Dammam, Saudi Arabia.
Eur J Orthod. 2017 Nov 30;39(6):595-600. doi: 10.1093/ejo/cjw091.
The aim of this clinical trial was to investigate the duration of mandibular-crowding alleviation with piezotome-corticision orthodontics compared with conventional orthodontics.
Single-centre, two-arm parallel group randomized controlled trial.
Orthodontic clinic at the University of Connecticut.
The study was approved by the Institutional Review Board (IRB # 12-0147-2).
Forty-one adult subjects from a single centre with more than 5mm of mandibular anterior crowding were randomly allocated using block randomization into experimental and control groups. The experimental group received a corticision procedure with a piezotome on the labial aspect of the mandibular incisors in conjunction to a self-ligation fixed orthodontic appliance. The control group received the self-ligation fixed orthodontic appliance and no corticision. Same archwire sequence (0.014 inch followed by 0.014 × 0.025 inch copper-nickel-titanium) was followed for both groups. Mandibular study casts taken every 4-5 weeks were used to assess changes in the irregularity index by blinded outcome assessors.
The time to alignment was calculated in days.
Twenty-nine subjects (16 experimental and 13 control) completed the study. Overall, no significant difference in the time required to correct mandibular crowding with piezotome-corticision assisted (102.1 ± 34.7 days; 95% CI, 83.6 to 120.6) and conventional orthodontics (112 ± 46.2 days; 95% CI, 84-139.9) was observed. No complications with treatment or unintended consequences were observed on any of the subjects.
A high attrition rate.
This randomized clinical trial found no evidence that piezotome-corticision assisted orthodontics was more efficient in alleviating mandibular anterior crowding.
ClinicalTrials.gov, Identifier: NCT02026258.
Division of Orthodontics, University of Connecticut.
None.
本临床试验旨在研究与传统正畸治疗相比，超声骨刀皮质切开术辅助正畸治疗缓解下颌拥挤的持续时间。
单中心、双臂平行组随机对照试验。
康涅狄格大学正畸诊所。
本研究经机构审查委员会批准（IRB编号：12 - 0147 - 2）。
来自单一中心的41名成年受试者，下颌前牙拥挤超过5mm，采用区组随机化方法随机分为实验组和对照组。实验组在使用自锁式固定正畸矫治器的同时，在下颌切牙唇侧进行超声骨刀皮质切开术。对照组仅接受自锁式固定正畸矫治器，不进行皮质切开术。两组均采用相同的弓丝序列（0.014英寸，随后是0.014×0.025英寸的铜镍钛合金弓丝）。每4 - 5周取下颌研究模型，由盲法结果评估者评估不规则指数的变化。
以天数计算排齐所需时间。
29名受试者（16名实验组和13名对照组）完成了研究。总体而言，观察到超声骨刀皮质切开术辅助正畸治疗（102.1±34.7天；95%CI，83.6至120.6）和传统正畸治疗（112±46.2天；95%CI，84 - 139.9）在纠正下颌拥挤所需时间上无显著差异。未观察到任何受试者出现治疗并发症或意外后果。
脱落率高。
这项随机临床试验未发现证据表明超声骨刀皮质切开术辅助正畸治疗在缓解下颌前牙拥挤方面更有效。
ClinicalTrials.gov标识符：NCT02026258。
康涅狄格大学正畸科。
无。
