Traditional Medicine and History of Medical Sciences Research Center, Department of Traditional Iranian Medicine, School of Traditional Iranian Medicine, Babol University of Medical Sciences, Babol, Iran.
Department of Clinical Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Daru. 2017 Apr 4;25(1):7. doi: 10.1186/s40199-017-0173-1.
Pharmacogenomics and pharmacoproteomics are new sciences that their goal is achieving therapeutics with maximum results and minimal side effects for each individual due to the pattern of his genome and proteome.Although they considered new and high technology sciences but in distant past, Persian sages like Avicenna also knew about importance of "personalized medicine" and used specific patterns to detect individual differences in order to select suitable medication.Based on experience and analogy they divided individuals into different categories considering characteristics like body color, body temperature, sleep-awake pattern and skeletal structure.They also paid attention to effect of environmental conditions such as climate, job and the change of seasons on the influence of medication.Considering the low cost and ease of use of these experiences, it seems that researching their opinions can uncover the historical roots of modern pharmacoproteomics and can possibly infuse new ideas in this field.
药物基因组学和药物蛋白质组学是新兴科学，它们的目标是根据个体的基因组和蛋白质组模式，为每个人实现最大疗效和最小副作用的治疗方法。尽管它们被认为是新的高科技科学，但在遥远的过去，像阿维森纳这样的波斯圣贤也知道“个性化医学”的重要性，并使用特定模式来检测个体差异，以选择合适的药物。基于经验和类比，他们根据身体颜色、体温、睡眠-觉醒模式和骨骼结构等特征将个体分为不同类别。他们还注意到环境条件（如气候、工作和季节变化）对药物影响的作用。考虑到这些经验的低成本和易用性，研究它们的观点似乎可以揭示现代药物蛋白质组学的历史根源，并可能为该领域注入新的思想。
