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在低能量、高碳水化合物、低脂肪饮食中添加纤维,对于新诊断出的超重II型糖尿病患者的治疗是否有任何益处?

Does adding fibre to a low energy, high carbohydrate, low fat diet confer any benefit to the management of newly diagnosed overweight type II diabetics?

作者信息

Beattie V A, Edwards C A, Hosker J P, Cullen D R, Ward J D, Read N W

机构信息

Dietetic Department, Royal Hallamshire Hospital, Sheffield.

出版信息

Br Med J (Clin Res Ed). 1988 Apr 23;296(6630):1147-9. doi: 10.1136/bmj.296.6630.1147.

Abstract

The effect of supplementing a low energy (roughly 5.0 MJ), high carbohydrate (180 g), low fat (roughly 25 g) diet with 10-15 g of either cereal fibre or guar gum was investigated in 24 newly diagnosed overweight non-insulin-dependent (type II) diabetics. The patients were divided into three treatment groups: one received a low fibre control diet throughout the study period of 20 weeks and the other received two supplements of cereal fibre and guar gum in a crossover manner. The nutrient content of the diets was kept constant throughout. Though patients taking the low fibre diet showed a smaller reduction in fasting plasma glucose concentrations over the first eight weeks than patients taking a high fibre diet, this difference was not evident at the end of 20 weeks; reductions in weight and glycated haemoglobin values were similar for each dietary regimen throughout the trial. There was little evidence that supplementing a low energy, high carbohydrate diet with fibre confers any therapeutic benefit to type II diabetics and no evidence that taking fibre as viscous polysaccharides is any more beneficial to overweight diabetics than taking a similar fibre supplement as cereal. On the contrary, guar gum caused more abdominal discomfort and flatulence than the other diets.

摘要

对24名新诊断出的超重非胰岛素依赖型(II型)糖尿病患者,研究了在低能量(约5.0兆焦耳)、高碳水化合物(180克)、低脂肪(约25克)饮食中添加10 - 15克谷物纤维或瓜尔豆胶的效果。患者被分为三个治疗组:一组在整个20周的研究期间接受低纤维对照饮食,另一组以交叉方式接受两种谷物纤维和瓜尔豆胶补充剂。整个过程中饮食的营养成分保持不变。尽管在最初八周内,食用低纤维饮食的患者空腹血糖浓度的降低幅度小于食用高纤维饮食的患者,但在20周结束时这种差异并不明显;在整个试验过程中,每种饮食方案的体重减轻和糖化血红蛋白值的降低情况相似。几乎没有证据表明在低能量、高碳水化合物饮食中添加纤维能给II型糖尿病患者带来任何治疗益处,也没有证据表明将纤维作为粘性多糖摄入对超重糖尿病患者比摄入类似的谷物纤维补充剂更有益。相反,与其他饮食相比,瓜尔豆胶导致更多的腹部不适和肠胃胀气。

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Dietary fibre, diabetes and obesity.
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Dietary fibre in type II diabetes.II型糖尿病中的膳食纤维
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本文引用的文献

3
Dietary fibre supplementation of a 'normal' breakfast administered to diabetics.
Diabetologia. 1980 May;18(5):379-83. doi: 10.1007/BF00276818.
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Food fibre as an obstacle to energy intake.
Lancet. 1973 Dec 22;2(7843):1418-21. doi: 10.1016/s0140-6736(73)92806-7.
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The two-period cross-over clinical trial.两阶段交叉临床试验。
Br J Clin Pharmacol. 1979 Jul;8(1):7-20. doi: 10.1111/j.1365-2125.1979.tb05903.x.

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