探索癌症中生殖系基因组与体细胞基因组之间的联系。
Exploring the Link between the Germline and Somatic Genome in Cancer.
作者信息
Geeleher Paul, Huang R Stephanie
机构信息
Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, Illinois.
出版信息
Cancer Discov. 2017 Apr;7(4):354-355. doi: 10.1158/2159-8290.CD-17-0192.
Abstract
Carter and colleagues propose a systematic analysis of the germline and somatic genome in cancer. They identify interactions that occur between germline and somatic variants. This elucidates the function of the germline genome in the context of cancer risk and development. .
摘要
卡特及其同事提议对癌症中的种系基因组和体细胞基因组进行系统分析。他们确定了种系变异和体细胞变异之间发生的相互作用。这阐明了种系基因组在癌症风险和发展背景下的功能。
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