Grissom Colin K, Jones Barbara E
1 Pulmonary and Critical Care Medicine, Intermountain Medical Center , Murray, Utah.
2 Pulmonary and Critical Care Medicine, The University of Utah , Salt Lake City, Utah.
High Alt Med Biol. 2018 Jun;19(2):109-115. doi: 10.1089/ham.2016.0142. Epub 2017 Apr 4.
Grissom, Colin K., and Barbara E. Jones. Respiratory health benefits and risks of living at moderate altitude. High Alt Med Biol 19:109-115, 2018.-The respiratory system plays a critical role in the series of physiologic responses that occur at high altitude and allows individuals to adapt to and tolerate hypobaric hypoxia. Persons with underlying lung disease may have complications, but sometimes derive benefits, related to residence at high altitude. This review will focus on health benefits and risks of patients with underlying asthma, chronic obstructive pulmonary disease, pulmonary hypertension, or obstructive sleep apnea, who live at altitudes of 1500 to 4500 m. We will also discuss maladaptive responses of the respiratory system at high altitude in previously healthy persons, including development of pulmonary hypertension and sleep-disordered breathing.
格里森姆，科林·K.，和芭芭拉·E.琼斯。生活在中等海拔高度对呼吸健康的益处和风险。《高海拔医学与生物学》19:109 - 115，2018年。——呼吸系统在高海拔地区发生的一系列生理反应中起着关键作用，并使个体能够适应和耐受低压缺氧。患有基础肺部疾病的人可能会出现并发症，但有时也会从居住在高海拔地区中获益。本综述将聚焦于患有基础哮喘、慢性阻塞性肺疾病、肺动脉高压或阻塞性睡眠呼吸暂停的患者，他们生活在海拔1500至4500米的高度。我们还将讨论以前健康的人在高海拔地区呼吸系统的适应不良反应，包括肺动脉高压和睡眠呼吸紊乱的发展。
