Bleijenberg Nienke, Smith Alexander K, Lee Sei J, Cenzer Irena Stijacic, Boscardin John W, Covinsky Kenneth E
Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, the Netherlands.
Department of General Practice Nursing Science, and University of Applied Sciences, Utrecht, the Netherlands.
J Am Geriatr Soc. 2017 Jul;65(7):1455-1461. doi: 10.1111/jgs.14819. Epub 2017 Apr 5.
Difficulty managing medicines and finances becomes increasingly common with advanced age, and compromises the ability to live safely and independently. Remarkably little is known how often this occurs.
To provide population-based estimates of the risk of developing incident difficulty managing medications and finances in older adults.
A prospective cohort study.
The Health and Retirement Study (HRS), a nationally representative study of older adults.
9,434 participants aged 65 and older who did not need help in managing medications or managing finances in 2002. Follow-up assessments occurred every 2 years until 2012.
The primary outcomes were time to difficulty managing medications and time to difficulty managing finances. Risk factors such as demographics, comorbidities, functional status, and cognitive status were assessed at baseline. Hazard models that considered the competing risk of death were used to estimate both the cumulative incidence of developing difficulty managing medications and finances and to identify potential risk factors. Analyses were adjusted for age, gender, race, marital status, wealth and education.
The 10 years incidence of difficulty increased markedly with age, ranging from 10.3% (95% CI 9.3-11.6) for managing medications and 23.1% (95% CI 21.6-24.7) for managing finances in those aged 65-69, to 38.2% (95% CI 33.4-43.5) for medicines and 69% (95% CI 63.7-74.3) for finances in those over age 85. Women had a higher probability of developing difficulty managing medications and managing finances than men.
This study highlights the importance of preparing older adults for the likelihood they will need assistance with managing their medicines and finances as the risk for having difficulty with these activities over time is substantial.
随着年龄增长,药物管理和财务管理困难变得越来越普遍,这损害了安全独立生活的能力。但对于这种情况发生的频率,人们所知甚少。
提供基于人群的老年人出现药物管理和财务管理困难风险的估计。
一项前瞻性队列研究。
健康与退休研究(HRS),一项具有全国代表性的老年人研究。
9434名65岁及以上的参与者,他们在2002年时不需要药物管理或财务管理方面的帮助。随访评估每2年进行一次,直至2012年。
主要结局是出现药物管理困难的时间和出现财务管理困难的时间。在基线时评估人口统计学、合并症、功能状态和认知状态等风险因素。使用考虑死亡竞争风险的风险模型来估计出现药物管理和财务管理困难的累积发生率,并识别潜在风险因素。分析针对年龄、性别、种族、婚姻状况、财富和教育进行了调整。
困难发生率在10年期间随年龄显著增加,65 - 69岁人群中药物管理困难的发生率为10.3%(95%可信区间9.3 - 11.6),财务管理困难的发生率为23.1%(95%可信区间21.6 - 24.7);85岁以上人群中药物管理困难的发生率为38.2%(95%可信区间33.4 - 43.5),财务管理困难的发生率为69%(95%可信区间63.7 - 74.3)。女性出现药物管理困难和财务管理困难的可能性高于男性。
本研究强调了让老年人为可能需要药物和财务管理方面的帮助做好准备的重要性,因为随着时间推移,这些活动出现困难的风险很大。