Hseuh C, Reyes C V
Veterans Administration Hospital, Hines, Illinois.
Am Fam Physician. 1988 Jun;37(6):129-32.
Progressive multifocal leukoencephalopathy, a demyelinating disease of the central nervous system, is caused by a polyomavirus. This opportunistic virus is demonstrable in affected brain tissue obtained by biopsy or at autopsy. The disease commonly occurs in immunocompromised patients secondary to lymphoproliferative disease, immunosuppressive therapy, autoimmune disorders and acquired immunodeficiency syndrome. The prognosis is poor.
进行性多灶性白质脑病是一种中枢神经系统脱髓鞘疾病,由多瘤病毒引起。这种机会性病毒在通过活检或尸检获取的受影响脑组织中可被检测到。该疾病常见于继发于淋巴增殖性疾病、免疫抑制治疗、自身免疫性疾病和获得性免疫缺陷综合征的免疫功能低下患者。预后较差。