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Errors between sites in restriction site mapping.

作者信息

Dix T I, Kieronska D H

机构信息

Department of Computer Science, University of Western Australia, Nedlands.

出版信息

Comput Appl Biosci. 1988 Mar;4(1):117-23. doi: 10.1093/bioinformatics/4.1.117.

DOI:10.1093/bioinformatics/4.1.117
PMID:2838134
Abstract

Restriction site mapping programs construct maps by generating permutations of fragments and checking for consistency. Unfortunately many consistent maps often are obtained within the experimental error bounds, even though there is only one actual map. A particularly efficient algorithm is presented that aims to minimize error bounds between restriction sites. The method is generalized for linear and circular maps. The time complexity is derived and execution times are given for multiple enzymes and a range of error bounds.

摘要

相似文献

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Errors between sites in restriction site mapping.
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引用本文的文献

1
A partial digest approach to restriction site mapping.一种用于限制酶切位点图谱绘制的部分酶切方法。
Bull Math Biol. 1994 Mar;56(2):275-94. doi: 10.1007/BF02460643.