Rha Eun Young, Kim Ho Jun, Han Kyungdo, Park Yongkyu, Yoo Gyeol
Department of Plastic and Reconstructive Surgery, Incheon St. Mary's Hospital Department of Biostatistics Department of Plastic and Reconstructive Surgery, Yeouido St. Mary's hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Medicine (Baltimore). 2017 Apr;96(14):e5385. doi: 10.1097/MD.0000000000005385.
Alcohol-related injuries have been concerned worldwide. However, there have been no large cross-sectional epidemiologic studies. The aim of this study was to investigate the association between alcohol and the prevalence of injury according to gender in a representative sample of the South Korean population. This cross-sectional study was based on data obtained in the Korea National Health and Nutrition Examination Survey from 2010 to 2012. In total, 15,249 Korean adults (7128 men and 8112 women) aged 19 years or older were enrolled. Injury was defined as the incidence of an injury or intoxication within the year before completing the survey questionnaire. Univariate and multiple logistic regression analyses were conducted to analyze the relationship between alcohol consumption and the prevalence of injury. Heavy alcohol consumption and high-risk drinking were associated with a higher prevalence of injury in women (adjusted odds ratio [aOR] and corresponding 95% confidence interval [CI]: 2.48 [1.321, 4.656], 1.816 [1.136, 2.929], respectively), and Alcohol Use Disorders Identification Test (AUDIT) scores ≥20 were associated with a higher prevalence of injury in both men and women (aOR and 95% CI: 1.425 [1.004, 2.024] and 3.71 [2.067, 6.66], respectively). According to the AUDIT scores results, women who were injured reported significantly more high-risk drinking behaviors per month compared with those who were not injured. Gender disparities in the relationship between alcohol and the prevalence of injury were found. Indeed, future research using a prospective design should examine the causal relationship between alcohol consumption and the prevalence injury according to gender to confirm that alcohol is a risk factor for injury and to identify the possible mechanisms underlying this phenomenon.
与酒精相关的伤害已引起全球关注。然而，此前尚无大规模的横断面流行病学研究。本研究旨在在韩国具有代表性的人群样本中，依据性别调查酒精与伤害患病率之间的关联。这项横断面研究基于2010年至2012年韩国国家健康与营养检查调查所获得的数据。总共纳入了15249名19岁及以上的韩国成年人（7128名男性和8112名女性）。伤害定义为在完成调查问卷前一年之内发生的受伤或中毒事件。采用单因素和多因素逻辑回归分析来分析饮酒与伤害患病率之间的关系。重度饮酒和高危饮酒与女性较高的伤害患病率相关（校正比值比[aOR]及相应的95%置信区间[CI]分别为：2.48[1.321,4.656]、1.816[1.136,2.929]），酒精使用障碍识别测试（AUDIT）得分≥20与男性和女性较高的伤害患病率均相关（aOR和95%CI分别为：1.425[1.004,2.024]和3.71[2.067,6.66]）。根据AUDIT得分结果，受伤女性每月报告的高危饮酒行为明显多于未受伤女性。研究发现了酒精与伤害患病率之间关系中的性别差异。事实上，未来采用前瞻性设计的研究应根据性别检验饮酒与伤害患病率之间的因果关系，以确认酒精是伤害的危险因素，并确定这一现象背后可能的机制。
