Wang Lin-Nan, Wang Lei, Liu Li-Min, Song Yue-Ming, Li Yue, Liu Hao
Department of Orthopedics, West China Hospital, Sichuan University Department of Orthopedics, Sichuan Orthopaedic Hospital, Chengdu, China.
Medicine (Baltimore). 2017 Apr;96(14):e6559. doi: 10.1097/MD.0000000000006559.
In its typical form, spinal tuberculosis (TB) presents as destroyed contiguous vertebral bodies with involvement of intervertebral discs and paravertebral or psoas abscesses. Atypical forms are uncommonly reported. Here, we describe 8 patients with noncontiguous multisegmental spinal TB with no intervertebral disc involvement. From 2013 to 2014, we surgically treated 384 patients with spinal TB to relieve spinal cord compression, re-establish spinal stability, confirm the diagnosis, and debride the TB foci. Eight of these patients had noncontiguous multisegmental TB without intervertebral disc involvement. Seven of the 8 patients underwent short-segmental fixation and fusion at a single focus. Appropriate combinations of anti-TB medication were continued until final follow-up. They were followed at established intervals using plain radiography, 3-dimensional computed tomography, and magnetic resonance imaging of the surgical region to evaluate fusion and the condition of the foci. Mean follow-up was 26.6 months (range, 24-32 months), during which time all patients were prescribed the appropriate anti-TB medications. Satisfactory clinical and radiological results were obtained in all patients, without complications. Presentation of noncontiguous multisegmental spinal TB without the involvement of intervertebral disc resembles that of a neoplasm or other spinal infection. Differentiation requires the presence of a combination of general symptoms, laboratory test results, appropriate radiological results, and the physician's experience. For patients in whom surgery is indicated, the patient's general condition should be taken into consideration. Surgical intervention only focus on the responsible level is less invasive and can achieve satisfactory clinical and radiographic outcomes.
典型的脊柱结核表现为相邻椎体破坏,椎间盘、椎旁或腰大肌脓肿受累。非典型形式的报道较少。在此,我们描述了8例非相邻多节段脊柱结核患者,其椎间盘未受累。2013年至2014年,我们对384例脊柱结核患者进行了手术治疗,以缓解脊髓压迫、重建脊柱稳定性、确诊并清除结核病灶。其中8例患者为非相邻多节段结核,椎间盘未受累。8例患者中的7例在单个病灶处接受了短节段固定融合术。持续使用适当的抗结核药物联合治疗直至最终随访。定期使用X线平片、三维计算机断层扫描和手术区域的磁共振成像对患者进行随访,以评估融合情况和病灶状况。平均随访时间为26.6个月(范围24 - 32个月),在此期间所有患者均服用了适当的抗结核药物。所有患者均获得了满意的临床和影像学结果,无并发症发生。非相邻多节段脊柱结核且椎间盘未受累的表现类似于肿瘤或其他脊柱感染。鉴别需要综合考虑全身症状、实验室检查结果、适当的影像学结果以及医生的经验。对于有手术指征的患者,应考虑患者的全身状况。仅针对责任节段进行手术干预创伤较小,可取得满意的临床和影像学效果。