Sivalingam Jaiganesh, Kumar Anil
Assistant Professor, Department of Radiodiagnosis, Meenakshi Medical College Hospital and Research Institute , Kanchipuram, India .
Consultant Radiologist, Vidya Health Imaging , Gwalior, MP, India .
J Clin Diagn Res. 2015 Nov;9(11):TC01-3. doi: 10.7860/JCDR/2015/14030.6719. Epub 2015 Nov 1.
Tuberculous spondylitis is one of the commonest forms of skeletal tuberculosis in developing countries like India causing significant morbidity due to compression of spinal cord and adjacent nerve roots. Diagnosis and intervention at early stage can prevent permanent damage such as spinal deformity and neurological deficits.
The purpose of this study was to demonstrate atypical MRI features in cases of tubercular spondylitis resembling neoplastic lesions and to stress that tuberculous spondylitis should be one of the differential diagnoses in any spinal pathology especially in developing countries.
This was a prospective study done in the patients diagnosed as tuberculous spondylitis on 0.2 T Siemens MRI between June 2011 and December 2014 in a tertiary care hospital in India. Total 529 cases of tubercular spinal lesions were diagnosed. Out of which only 59 patients showed atypical features on MR imaging which resembled neoplastic lesions were included in the study. The diagnosis was confirmed by cytology, histopathology, serology and corroborative findings.
Lumbo-sacral region involvement (30.5%) is the commonest in our study followed by dorsal and cervical region. Multiple level lesions are seen in 14 cases (23.7%). All the 59 (100%) cases show no involvement of intervetebral disc. Posterior appendage involvement seen in 32 cases (54.2%). Soft tissue component seen in Intraspinal (37.2%) and paraspinal (45.7%) compartments. Cord compression seen in 19 cases (32.2%), out which only 7 cases (11.8%) shows cord oedema.
On MRI, tubercular spondylitis may have variable pictures on imaging. For any spinal and paraspinal lesions, we should also consider the possibility of tubercular aetiology along with other. Since early diagnosis avoids unnecessary delay in the treatment thereby reducing morbidity and possible complications.
在印度等发展中国家,结核性脊柱炎是骨骼结核最常见的形式之一,由于脊髓和相邻神经根受压可导致显著的发病率。早期诊断和干预可预防诸如脊柱畸形和神经功能缺损等永久性损伤。
本研究的目的是展示结核性脊柱炎病例中类似肿瘤病变的非典型MRI特征,并强调在任何脊柱病变中,尤其是在发展中国家,结核性脊柱炎都应作为鉴别诊断之一。
这是一项前瞻性研究,于2011年6月至2014年12月在印度一家三级护理医院对经0.2 T西门子MRI诊断为结核性脊柱炎的患者进行。共诊断出529例结核性脊柱病变。其中只有59例患者在MR成像上表现出类似肿瘤病变的非典型特征,被纳入本研究。诊断通过细胞学、组织病理学、血清学及相关发现得以证实。
在我们的研究中,腰骶部受累(30.5%)最为常见,其次是背部和颈部区域。14例(23.7%)可见多节段病变。所有59例(100%)病例均未累及椎间盘。32例(54.2%)可见后部附件受累。脊髓内(37.2%)和椎旁(45.7%)间隙可见软组织成分。19例(32.2%)可见脊髓受压,其中只有7例(11.8%)表现出脊髓水肿。
在MRI上,结核性脊柱炎在影像学上可能有多种表现。对于任何脊柱和椎旁病变,我们除了考虑其他病因外,还应考虑结核病因的可能性。因为早期诊断可避免治疗中不必要的延误,从而降低发病率及可能的并发症。