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2007年至2014年维多利亚州哨点监测全科诊所的流感检测趋势

Influenza testing trends in sentinel surveillance general practices in Victoria 2007 to 2014.

作者信息

Cowie Genevieve A, Cowie Benjamin C, Fielding James E

机构信息

Doctor of Public Health candidate, Department of Epidemiology, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria.

Director, WHO Collaborating Centre for Viral Hepatitis, VIDRL, Doherty Institute for Infection and Immunity, Melbourne, Victoria.

出版信息

Commun Dis Intell Q Rep. 2017 Mar 31;41(1):E4-E9. doi: 10.33321/cdi.2017.41.2.

Abstract

The Victorian Sentinel Practice Influenza Network conducts syndromic surveillance for influenza-like illness (ILI), with testing for laboratory confirmation of a proportion of cases at the discretion of general practitioners. The aim of this study was to evaluate the consistency of sentinel general practitioners' swabbing practice within and between influenza seasons. Aggregated, weekly, non-identified data for May to October each year from 2007 to 2014 were used to calculate the proportion of patients presenting with ILI (defined as cough, fever and fatigue), proportion of ILI patients swabbed and proportion of swabs positive for influenza. Data on the proportion of consultations for ILI and the proportion of ILI patients swabbed were aggregated into time-period quintiles for each year. Analysis of variance was used to compare ILI patients swabbed for each aggregated time-period quintile over all 8 years. Spearman's correlation and Bland-Altman analyses were used to measure association and agreement respectively between ILI proportions of consultations and swabs positive for influenza in time period quintiles within each year. Data were aggregated by year for the rest of the analyses. Between 2007 and 2014 there was a slight decrease in the proportion of positive tests and the proportion of ILI patients was generally a good proxy for influenza test positivity. There was consistency in testing within and between seasons, despite an overall testing increase between 2007 and 2014. There was no evidence for temporal sampling bias in these data despite testing not being performed on a systematic basis. This sampling regimen could also be considered in other similar surveillance systems.

摘要

维多利亚哨兵实践流感监测网络对流感样疾病(ILI)进行症状监测,由全科医生自行决定对部分病例进行实验室确诊检测。本研究的目的是评估流感季节内和季节间哨兵全科医生拭子采样操作的一致性。使用2007年至2014年每年5月至10月汇总的、每周的、匿名数据,计算出现ILI(定义为咳嗽、发热和乏力)的患者比例、接受拭子采样的ILI患者比例以及流感拭子检测呈阳性的比例。每年将ILI咨询比例和接受拭子采样的ILI患者比例数据汇总为时间段五分位数。方差分析用于比较所有8年中每个汇总时间段五分位数的接受拭子采样的ILI患者情况。Spearman相关性分析和Bland-Altman分析分别用于测量每年时间段五分位数内ILI咨询比例与流感拭子检测阳性比例之间的关联和一致性。其余分析按年份汇总数据。2007年至2014年期间,检测阳性比例略有下降,ILI患者比例通常是流感检测阳性的良好指标。尽管2007年至2014年期间总体检测量增加,但季节内和季节间的检测具有一致性。尽管检测并非基于系统的基础进行,但这些数据中没有证据表明存在时间抽样偏差。其他类似的监测系统也可考虑采用这种采样方案。

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