Zoia A, Drigo M
San Marco Veterinary Clinic, via Sorio 114c, Italy.
Department of Animal Medicine, Production and Health, Padua University, Agripolis, Viale dell'Università 16, Padua, Italy.
J Comp Pathol. 2017 May;156(4):384-388. doi: 10.1016/j.jcpa.2017.02.003. Epub 2017 Apr 3.
In most cases, the underlying causes of feline pancreatitis and feline immune-mediated haemolytic anaemia (IMHA) remain unknown. Following the observation that some cats present with both diseases concurrently, the aim of this cross-sectional study was to investigate if the two disorders were associated statistically in this species. A residency case log of all cases seen at the Small Animal Hospital, University of Glasgow, Glasgow, UK, between July 2004 and December 2007, was used as the database for this study and an association between these two disorders was assessed by Fisher's exact test. Of the 155 sick cats included in the study, nine were diagnosed at the time of presentation with pancreatitis (prevalence of 5.8%) and 11 with IMHA (prevalence of 7.1%). In three of these cats both conditions were present concurrently at the time of presentation (prevalence of 1.9%). A significant association between these two disease was found (Odds Risk 8.63, exact 95% confidence interval 1.15-49.31, P = 0.0178). Two possible biological explanations for the statistical association found between these two diseases are that one of these conditions may represent the cause for the onset of the other or that an underlying disorder of the immune system may concurrently target feline red blood cells and the exocrine pancreas.
在大多数情况下，猫胰腺炎和猫免疫介导性溶血性贫血（IMHA）的潜在病因仍不清楚。在观察到一些猫同时患有这两种疾病后，这项横断面研究的目的是调查这两种疾病在该物种中是否存在统计学关联。英国格拉斯哥大学小动物医院2004年7月至2007年12月期间诊治的所有病例的住院病例记录被用作本研究的数据库，并通过Fisher精确检验评估这两种疾病之间的关联。在纳入研究的155只病猫中，9只在就诊时被诊断为胰腺炎（患病率为5.8%），11只被诊断为IMHA（患病率为7.1%）。其中3只猫在就诊时同时患有这两种疾病（患病率为1.9%）。发现这两种疾病之间存在显著关联（优势风险8.63，精确95%置信区间1.15 - 49.31，P = 0.
