Klinik für Allgemein-, Viszeral- und Onkologische Chirurgie, Klinikum St. Georg gGmbH, Delitzscher Straße 141, 04129 Leipzig, Germany.
San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy.
Clin Nutr. 2017 Jun;36(3):623-650. doi: 10.1016/j.clnu.2017.02.013. Epub 2017 Mar 7.
Early oral feeding is the preferred mode of nutrition for surgical patients. Avoidance of any nutritional therapy bears the risk of underfeeding during the postoperative course after major surgery. Considering that malnutrition and underfeeding are risk factors for postoperative complications, early enteral feeding is especially relevant for any surgical patient at nutritional risk, especially for those undergoing upper gastrointestinal surgery. The focus of this guideline is to cover nutritional aspects of the Enhanced Recovery After Surgery (ERAS) concept and the special nutritional needs of patients undergoing major surgery, e.g. for cancer, and of those developing severe complications despite best perioperative care. From a metabolic and nutritional point of view, the key aspects of perioperative care include: • integration of nutrition into the overall management of the patient • avoidance of long periods of preoperative fasting • re-establishment of oral feeding as early as possible after surgery • start of nutritional therapy early, as soon as a nutritional risk becomes apparent • metabolic control e.g. of blood glucose • reduction of factors which exacerbate stress-related catabolism or impair gastrointestinal function • minimized time on paralytic agents for ventilator management in the postoperative period • early mobilisation to facilitate protein synthesis and muscle function The guideline presents 37 recommendations for clinical practice.
早期口服喂养是外科患者首选的营养方式。避免任何营养治疗都有可能导致大手术后术后期间出现喂养不足。考虑到营养不良和喂养不足是术后并发症的危险因素,因此对于任何有营养风险的外科患者,尤其是接受上消化道手术的患者,早期肠内喂养尤其重要。本指南的重点是涵盖手术患者的加速康复外科(ERAS)概念的营养方面以及接受重大手术患者(例如癌症患者)和尽管接受最佳围手术期护理但仍出现严重并发症患者的特殊营养需求。从代谢和营养的角度来看,围手术期护理的关键方面包括:
将营养纳入患者整体管理中
避免长时间术前禁食
术后尽早恢复口服喂养
一旦出现营养风险,尽早开始营养治疗
代谢控制,例如血糖控制
减少应激相关分解代谢或损害胃肠道功能的因素
在术后期间使用肌肉松弛剂进行呼吸机管理的时间最短
早期活动以促进蛋白质合成和肌肉功能
本指南提出了 37 条临床实践建议。