Protection of mice from lethal infection with Aujeszky's disease virus by immunization with purified gVI.
作者信息
Ishii H, Kobayashi Y, Kuroki M, Kodama Y
机构信息
Ghen Corporation, Gifu Laboratory, Japan.
出版信息
J Gen Virol. 1988 Jun;69 ( Pt 6):1411-4. doi: 10.1099/0022-1317-69-6-1411.
PMID:2838579
Abstract
Virus envelope glycoprotein gVI (gp50) of Aujeszky's disease virus (ADV) was purified from a Nonidet P40-solubilized lysate of ADV-infected Vero cells by immunoaffinity chromatography using a monoclonal antibody against gVI. Mice immunized by the purified gVI produced virus-neutralizing antibody and were successfully protected against subsequent challenge with ADV.
摘要
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