Cerkez Idris, Sezer Ayse, Bhullar Sukhwinder K
Department of Fiber and Polymer Engineering , Bursa Technical University , Bursa, 16190 , Turkey.
Department of Mechanical Engineering , Bursa Technical University , Bursa, 16190 , Turkey.
R Soc Open Sci. 2017 Feb 8;4(2):160911. doi: 10.1098/rsos.160911. eCollection 2017 Feb.
This research study is mainly targeted on fabrication and characterization of antibacterial poly(e-caprolactone) (PCL) based fibrous membrane containing silver chloride particles. Micro/nano fibres were produced by electrospinning and characterized with TGA, DSC, SEM and mechanical analysis. It was found that addition of silver particles slightly reduced onset of thermal degradation and increased crystallization temperature of neat PCL. Silver-loaded samples exhibited higher tensile stress and lower strain revealing that the particles behaved as reinforcing agent. Moreover, addition of silver chloride resulted in beaded surface texture and formation of finer fibres as opposed to the neat. Antibacterial properties were tested against Gram-negative and Gram-positive bacteria and remarkable biocidal functionalities were obtained with about six logs reduction of and O157:H7.
本研究主要针对含氯化银颗粒的抗菌聚己内酯（PCL）基纤维膜的制备与表征。通过静电纺丝制备了微/纳米纤维，并采用热重分析（TGA）、差示扫描量热法（DSC）、扫描电子显微镜（SEM）和力学分析对其进行了表征。研究发现，银颗粒的加入略微降低了纯PCL的热降解起始温度，并提高了其结晶温度。载银样品表现出更高的拉伸应力和更低的应变，这表明颗粒起到了增强剂的作用。此外，与纯PCL相比，氯化银的加入导致表面形成珠状纹理并形成更细的纤维。对革兰氏阴性菌和革兰氏阳性菌进行了抗菌性能测试，结果显示具有显著的杀菌功能，对大肠杆菌O157:H7的杀灭率约为6个对数级。
