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伴脊髓栓系的腰骶部脂肪瘤的神经外科治疗与病理学

Neurosurgical management and pathology of lumbosacral lipomas with tethered cord.

作者信息

Morioka Takato, Murakami Nobuya, Shimogawa Takafumi, Mukae Nobutaka, Hashiguchi Kimiakai, Suzuki Satoshi O, Iihara Koji

机构信息

Department of Neurosurgery, Fukuoka Children's Hospital, Fukuoka, Japan.

Department of Neurosurgery, Kyushu University, Fukuoka, Japan.

出版信息

Neuropathology. 2017 Oct;37(5):385-392. doi: 10.1111/neup.12382. Epub 2017 Apr 7.

Abstract

Lumbosacral lipomas are the most common form of occult spinal dysraphism. The development of lumbosacral lipomas is from the premature disjunction of the neural tube from the surrounding ectoderm, leaving the neural plate open posteriorly and allowing for the infiltration of mesodermal tissue, including fatty tissue. Since lumbosacral lipomas are a common cause of spinal cord tethering that can lead to progressive neurological deficits, prophylactic neurosurgery for lumbosacral lipomas, including untethering of the spinal cord, is recommended. We briefly review the embryology, classification, clinical presentation, imaging evaluation, surgical indication, neurosurgical management and pathological examination that are involved in recognizing these complicated malformative pathologies.

摘要

腰骶部脂肪瘤是隐性脊柱裂最常见的形式。腰骶部脂肪瘤的发生源于神经管与周围外胚层过早分离,使神经板后部开放,从而允许包括脂肪组织在内的中胚层组织浸润。由于腰骶部脂肪瘤是脊髓拴系的常见原因,可导致进行性神经功能缺损,因此建议对腰骶部脂肪瘤进行预防性神经外科手术,包括脊髓松解术。我们简要回顾了识别这些复杂畸形病变所涉及的胚胎学、分类、临床表现、影像学评估、手术指征、神经外科治疗及病理检查。

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