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冷信号从膜到核穿梭。

Cold Signal Shuttles from Membrane to Nucleus.

机构信息

Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; University of Chinese Academy of Sciences, Beijing 100093, China.

Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; University of Chinese Academy of Sciences, Beijing 100093, China; National Center for Plant Gene Research, Beijing 100093, China.

出版信息

Mol Cell. 2017 Apr 6;66(1):7-8. doi: 10.1016/j.molcel.2017.03.010.

DOI:10.1016/j.molcel.2017.03.010
PMID:28388442
Abstract

In this issue of Molecular Cell, Liu et al. (2017) show that the cold-activated plasma membrane protein kinase CRPK1 phosphorylates 14-3-3 proteins, triggering its nuclear translocation to impair the stabilization of the transcription factor CBFs for a feedback excessive cold defense response during the freezing in Arabidopsis.

摘要

在本期《分子细胞》中,刘等人(2017)表明,冷激活的质膜蛋白激酶 CRPK1 磷酸化 14-3-3 蛋白,触发其核转位,从而损害转录因子 CBFs 的稳定性,导致拟南芥在冷冻过程中产生过度的冷防御反应的反馈。

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2
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