身体活动而非久坐时间本身对社区居住老年女性的代谢综合征风险有影响。
Physical activity and not sedentary time per se influences on clustered metabolic risk in elderly community-dwelling women.
作者信息
Nilsson Andreas, Wåhlin-Larsson Britta, Kadi Fawzi
机构信息
School of Health Sciences, Örebro University, Örebro, Sweden.
出版信息
PLoS One. 2017 Apr 7;12(4):e0175496. doi: 10.1371/journal.pone.0175496. eCollection 2017.
INTRODUCTION
Whether amount of time spent in sedentary activities influences on clustered metabolic risk in elderly, and to what extent such an influence is independent of physical activity behavior, remain unclear. Therefore, the aim of the study was to examine cross-sectional associations of objectively assessed physical activity and sedentary behavior on metabolic risk outcomes in a sample of elderly community-dwelling women.
METHODS
Metabolic risk outcomes including waist circumference, systolic and diastolic blood pressures, fasting levels of plasma glucose, HDL-cholesterol and triglycerides were assessed in 120 community-dwelling older women (65-70 yrs). Accelerometers were used to retrieve daily sedentary time, breaks in sedentary time, daily time in light (LPA) and moderate-to-vigorous physical activity (MVPA), and total amount of accelerometer counts. Multivariate regression models were used to examine influence of physical activity and sedentary behavior on metabolic risk outcomes including a clustered metabolic risk score.
RESULTS
When based on isotemporal substitution modeling, replacement of a 10-min time block of MVPA with a corresponding time block of either LPA or sedentary activities was associated with an increase in clustered metabolic risk score (β = 0.06 to 0.08, p < 0.05), and an increase in waist circumference (β = 1.78 to 2.19 p < 0.01). All associations indicated between sedentary time and metabolic risk outcomes were lost once variation in total accelerometer counts was adjusted for.
CONCLUSIONS
Detrimental influence of a sedentary lifestyle on metabolic health is likely explained by variations in amounts of physical activity rather than amount of sedentary time per se. Given our findings, increased amounts of physical activity with an emphasis on increased time in MVPA should be recommended in order to promote a favorable metabolic health profile in older women.
引言
久坐活动所花费的时间是否会影响老年人的代谢风险聚集，以及这种影响在多大程度上独立于身体活动行为，目前尚不清楚。因此，本研究的目的是在一组社区居住的老年女性样本中，检验客观评估的身体活动和久坐行为与代谢风险结果之间的横断面关联。
方法
对120名社区居住的老年女性（65 - 70岁）进行了代谢风险指标评估，包括腰围、收缩压和舒张压、空腹血糖水平、高密度脂蛋白胆固醇和甘油三酯。使用加速度计来获取每日久坐时间、久坐时间的中断、轻度身体活动（LPA）和中度至剧烈身体活动（MVPA）的每日时间，以及加速度计计数的总量。使用多变量回归模型来检验身体活动和久坐行为对代谢风险结果（包括代谢风险聚集评分）的影响。
结果
基于等时替代模型，用相应的LPA或久坐活动时间块替换10分钟的MVPA时间块，与代谢风险聚集评分增加（β = 0.06至0.08，p < 0.05）以及腰围增加（β = 1.78至2.19，p < 0.01）相关。一旦对加速度计计数总量的变化进行调整，久坐时间与代谢风险结果之间的所有关联均消失。
结论
久坐生活方式对代谢健康的有害影响可能是由身体活动量的变化而非久坐时间本身所解释。根据我们的研究结果，为促进老年女性的良好代谢健康状况，应建议增加身体活动量，尤其要增加MVPA的时间。
Zotero 插件