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用于感染的单阶段翻修关节成形术——一种未充分利用的治疗策略。

Single-Stage Revision Arthroplasty for Infection-An Underutilized Treatment Strategy.

作者信息

Negus Jonathan J, Gifford Peter B, Haddad Fares S

机构信息

Department of Trauma and Orthopaedics, University College London Hospital, London, United Kingdom.

出版信息

J Arthroplasty. 2017 Jul;32(7):2051-2055. doi: 10.1016/j.arth.2017.02.059. Epub 2017 Mar 2.

Abstract

BACKGROUND

The burden of revision arthroplasty surgery for infection is rising as the rate of primary arthroplasty surgery increases. Infected arthroplasty rates are now relatively low, but the sheer increase in volume is leading to considerable patient morbidity and significant increases in costs to the health care system. Single-stage revision for infection is one of the several accepted treatment options, but the indications and results are debated. This review aims to clarify the current evidence.

METHODS

MEDLINE/PubMed databases were reviewed for studies that looked at single- or one-stage revision knee or hip arthroplasty for infection.

RESULTS

There is increasing evidence that single-stage revision for infection can control infection and with decreased morbidity, mortality, and health care costs compared with a staged approach. However, the indications are still debated. Recently, there has been a determined effort to define an infected arthroplasty in a manner that will allow for standardization of reporting in the literature. The evidence supporting single stage for knee arthroplasty is catching up with the result with hip arthroplasty. High-quality data from randomized controlled trials are now pending.

CONCLUSION

After the gradual evolution of using the single-stage approach, with the widespread acceptance of this definition, we can now standardize comparisons across the world and move toward a refined definition of the ideal patient population for single-stage arthroplasty revision in both the hip and the knee population.

摘要

背景

随着初次关节置换手术率的上升,因感染进行翻修关节置换手术的负担也在增加。目前感染性关节置换的发生率相对较低,但手术量的单纯增加导致了相当多的患者发病,并使医疗保健系统的成本大幅增加。感染的一期翻修是几种公认的治疗选择之一,但适应症和结果仍存在争议。本综述旨在阐明当前的证据。

方法

对MEDLINE/PubMed数据库进行检索,查找有关感染性膝关节或髋关节置换的单期或一期翻修的研究。

结果

越来越多的证据表明,与分期手术相比,感染的一期翻修可以控制感染,并降低发病率、死亡率和医疗保健成本。然而,适应症仍存在争议。最近,人们一直在努力以一种能够使文献报告标准化的方式来定义感染性关节置换。支持膝关节置换一期翻修的证据正在追赶髋关节置换的结果。目前正在等待来自随机对照试验的高质量数据。

结论

在单期手术方法逐渐演变之后,随着这一定义的广泛接受,我们现在可以在全球范围内标准化比较,并朝着为髋关节和膝关节人群的单期关节置换翻修确定理想患者群体的精确定义迈进。

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